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Phase 3 N=604 Double-blind Treatment

OTC Mouthpiece for Snoring

Snoring

Enrolled (actual)
604
Serious AEs
0.0%
Results posted
Dec 2017
Primary outcome: Primary: Snoring Severity Scale — -4.1 units on a scale — p=< 0.0001

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Zyppah Anti-snoring Appliance (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Zyppah, Inc.
Primary completion
May 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Snoring Severity Scale
-4.1 < 0.0001 sig
PRIMARY
Visual-Analogue Scale, Self-Reported Snoring Habits
-51.5; -60.2; -56.8 < 0.0001 sig

Summary

Online patient registration to participate in clinical trial to test OTC mouthpiece that controls position of the tongue to reduce snoring.

Eligibility Criteria

Inclusion Criteria

  • Over 18 years of age
  • Living in the United States
  • Signing the Informed Consent Form

Exclusion Criteria

  • Missing teeth (as the device won't be properly fitted)
  • Any severe breathing or respiratory disorder, such as chronic asthma, emphysema, COPD, or a similar condition
  • Poor dental health, such as severe gum disease, loose teeth, an abscess, mouth sores, or bleeding gums
  • A dental implant placed within the last three months
  • Diagnosed with a Temporomandibular joint condition (TMJ)
  • Actively experiencing any mouth or jaw pain, including clenching of the teeth, grinding, or any other physical injury to the jaw or teeth
  • Full dentures
  • Braces
  • Diagnosis of sleep apnea
  • Less than 18 years of age
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03128307). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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