N/A
N=266,499
Polypharmacy and Outcomes After Elective Noncardiac Surgery
Polypharmacy · Surgical Procedure, Operative · Morality · Epidemiology
Bottom Line
View on ClinicalTrials.gov: NCT03133182 ↗Enrolled (actual)
266,499
Serious AEs
—
Results posted
Jan 2025
Primary outcome: Primary: Mortality — 4356; 1919 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- Polypharmacy (Drug)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Ottawa Hospital Research Institute
- Primary completion
- Mar 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mortality |
4356; 1919 | — |
| SECONDARY Complications |
31570; 19815 | — |
| SECONDARY Length of Stay |
5; 5 | — |
| SECONDARY Costs of Care |
24064; 20251 | — |
| SECONDARY Institutional Discharge |
34128; 23098 | — |
| SECONDARY Hospital Readmission |
13202; 8097 | — |
Summary
This study investigates the association of preoperative polypharmacy with outcomes and healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program
Eligibility Criteria
Inclusion Criteria
- Intermediate to high risk elective non-cardiac surgery
- Age >=66 on day of surgery
Exclusion Criteria
-
Data sourced from ClinicalTrials.gov (NCT03133182). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.