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N/A Completed N=266,499

Polypharmacy and Outcomes After Elective Noncardiac Surgery

Polypharmacy · Surgical Procedure, Operative · Morality · Epidemiology
Source: ClinicalTrials.gov NCT03133182 ↗
Enrolled (actual)
266,499
Serious AEs
Results posted
Jan 2025
Primary outcomePrimary: Mortality — 4356; 1919 Participants

Summary

This study investigates the association of preoperative polypharmacy with outcomes and healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

Outcome Measures

OutcomeResultp-value
PRIMARY
Mortality
4356; 1919
SECONDARY
Complications
31570; 19815
SECONDARY
Length of Stay
5; 5
SECONDARY
Costs of Care
24064; 20251
SECONDARY
Institutional Discharge
34128; 23098
SECONDARY
Hospital Readmission
13202; 8097

Eligibility Criteria

Inclusion Criteria

  • Intermediate to high risk elective non-cardiac surgery
  • Age >=66 on day of surgery

Exclusion Criteria

-

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03133182). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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