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Phase 3 Completed N=147 Randomized Treatment

Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

video-assisted thoracoscopic surgery · Pain, Postoperative · Pain, Acute
Source: ClinicalTrials.gov NCT03151434 ↗
Enrolled (actual)
147
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcomePrimary: The Primary Endpoint of This Study Will be VAS Pain Score at 24 Hours — 4.0; 4.5; 3.0 units on a scale
◆ Published Evidence
Established
57citations · ~10 / year
Randomized Prospective Study Evaluating Single-Injection Paravertebral Block, Paravertebral Catheter, and Thoracic Epidural Catheter for Postoperative Regional Analgesia After Video-Assisted Thoracoscopic Surgery.
Journal of cardiothoracic and vascular anesthesia · 2020 · Open access · High-confidence link

Summary

The purpose of this study is to compare three different pain control methods on subjects who are scheduled to undergo VATS (video-assisted thoracoscopic surgery) procedures. The study will compare their pain scores, narcotic needs, patient satisfaction scores, and narcotic side effects.

Linked Publications

  • Randomized Prospective Study Evaluating Single-Injection Paravertebral Block, Paravertebral Catheter, and Thoracic Epidural Catheter for Postoperative Regional Analgesia After Video-Assisted Thoracoscopic Surgery.
    Journal of cardiothoracic and vascular anesthesia · 2020 · 57 citations · Open access · High-confidence link

Outcome Measures

OutcomeResultp-value
PRIMARY
The Primary Endpoint of This Study Will be VAS Pain Score at 24 Hours
4.0; 4.5; 3.0
PRIMARY
The Primary Endpoint of This Study Will be VAS Pain Score at 48 Hours
3.0; 4.0; 2.0
SECONDARY
Secondary Endpoint Includes Total Intravenous Opioid Consumption at 72 Hours
57; 35; 21.3

Eligibility Criteria

Inclusion Criteria

  • Pt undergoing VATS procedure at Indiana University Hospital
  • ASA 1,2,3 or 4
  • Age 18 or older, male or female
  • Desires Regional anesthesia for postoperative pain control

Exclusion Criteria

  • Any contraindication for Thoracic Epidural or Paravertebral block
  • History of substance abuse in the past 6 months
  • Patient staying intubated after surgery
  • Known allergy or other contraindications to the study medications , which include dilaudid, bupivacaine, ropivacaine
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03151434) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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