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N/A N=57 Randomized Quadruple-blind Treatment

Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms

Leg Cramp, Nocturnal

Enrolled (actual)
57
Serious AEs
0.0%
Results posted
Mar 2019
Primary outcome: Primary: Change in Restless Legs Syndrome Quality of Life Instrument (RLSQoL) Over 4 Weeks — 78.92; 80.75; 77.75; 83.16 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Theraworx (Device); Placebo (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Sport and Spine Rehab Clinical Research Foundation
Primary completion
Jun 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Restless Legs Syndrome Quality of Life Instrument (RLSQoL) Over 4 Weeks
78.92; 80.75; 77.75; 83.16; 87; 87.03
PRIMARY
Change in Beck Depression Scale Over 4 Weeks
12.4; 8.48; 9.56; 6.92; 6.88; 5.6
PRIMARY
Change in Pittsburgh Sleep Quality Index Over 4 Weeks
10.72; 10.12; 11; 9.52; 9.12; 7.8
PRIMARY
Change in Modified Patient Specific Functional Scale Over 4 Weeks
4.53; 5.76; 4.99; 6.59; 6.47; 7.4
SECONDARY
Change in Symptom Log Over 4 Weeks
5.12; 4.72; 4.72; 4.8; 4.44; 3.32

Summary

The purpose of this study is to determine the effect of Theraworx/[pH]uel on the frequency and severity of night-time cramps and spasms symptoms, including quality of life, depression and sleep quality when compared to a placebo.

Eligibility Criteria

Inclusion Criteria

  • Subjects who claim to have experienced night-time cramps and spasms on average at least three times per week

Exclusion Criteria

  • Individuals will be excluded from the study if they are pregnant, have been previously diagnosed with a non-RLS sleep disorder, previously diagnosed with schizophrenia or any other neurological disorder
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03159260). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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