N/A N=20 Randomized Single-blind Other

Effect of Local Anaesthetic Dilution on the Characteristics of Ultrasound Guided Axillary Brachial Plexus Block

Brachial Plexus Blockade

Bottom Line

View on ClinicalTrials.gov: NCT03207035 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2021

Primary outcome: Primary: Onset of Axillary Block — 8.75; 6.25 minutes — p=0.03

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Axillary brachial plexus block (Procedure)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Cork University Hospital
Primary completion: Mar 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Onset of Axillary Block	8.75; 6.25	0.03 sig
SECONDARY Duration of Sensory and Motor Block	165.1; 150.9	0.02 sig
SECONDARY Block Performance Data- Imaging Time	2.5; 2.4	0.70
SECONDARY Needling Time	8.5; 6.7	0.002 sig
SECONDARY Performance Time	10.9; 9.1	0.001 sig
SECONDARY No of Needle Pass	10.5; 9.1	0.001 sig
SECONDARY Vascular Puncture	2; 1	0.53
SECONDARY Parasthesia	4; 2	0.48

Summary

We propose to compare the effects of local anaesthetic dilution on the characteristics of the ultrasound guided axillary brachial plexus block. Administration of 40ml lidocaine 1% with epinephrine will shorten the onset time of ultrasound guided axillary brachial plexus block when compared to 20 mL lidocaine 2% with epinephrine for elective upper limb surgical procedures.

Eligibility Criteria

Inclusion Criteria

ASA 1-3
Patients aged >18 years undergoing elective upper limb (forearm or hand) surgical procedures.

Exclusion Criteria

Contraindications to regional anaesthesia
Hypersensitivity to amide local anaesthetics.
Chronic pain
Language barrier
Neuromuscular disorders or peripheral neuropathy
Body mass index > 35
History of hepatic and renal insufficiency
Pregnancy
Cognitive or psychiatric disorder
Cardiac conduction abnormality.

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Data sourced from ClinicalTrials.gov (NCT03207035). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.