The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)

Inclusion Criteria

• Must be able to read and understand the study informed consent
• Must be a minimum of 18 years of age and less than 46 years of age at study enrollment
• Must be healthy non-soft contact lens wearers (neophytes), or experienced contact lens wearers that have not worn their contact lenses for a minimum of 7 days
• Have a spherical equivalent refractive error between -0.75 to -6.50DS at the spectacle plane
• The subject must be able to attend study visits at the prescribed visit times and adhere to the study instructions

Exclusion Criteria

• Pregnant and/or lactating females by self-report
• Presence of current LWE on the upper eyelid (>0.5 in height or width)
• Has greater than -1.00DC of refractive cylinder
• Has greater than 1.00D of anisometropia
• Is aphakic
• Has clinically significant corneal or conjunctival staining that would prevent contact lens fitting, as assessed with sodium fluorescein dye
• Has significant ocular surface disease (e.g. Sjögrens Disease, Stevens-Johnson Syndrome, etc.) or significant Dry Eye Syndrome
• Has clinically significant corneal vascularization or central corneal scaring
• Has active ocular surface infection (e.g. conjunctivitis)
• Has a positive history of eyelid surgery or trauma
• Has a positive history of refractive surgery
• Takes medications that significantly impact contact lens comfort and/or ocular surface health
• Has taken part in another contact lens or contact lens solution clinical trial within the last 7 days
• Is unwilling to have eyes photographed or video recorded