N/A N=554 Randomized Single-blind Prevention

Communicating Multiple Disease Risks: A Translation of Risk Prediction Science

Healthy Volunteers

Bottom Line

View on ClinicalTrials.gov: NCT03255291 ↗

Enrolled (actual)

554

Serious AEs

—

Results posted

Jan 2020

Primary outcome: Primary: Change From Baseline to 90-day Follow-up in Self Reported Weekly Minutes of Exercise — 92.2; 37.5; 63.1; 60.0 minutes — p=0.0288

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Risk Assessment App (Behavioral); Audio Recording - Sleep (Behavioral); Surveys (Other); Audio Recording - Exercise (Behavioral); Text message reminders (Other); Text Message Survey (Other)
Age: Adult · 30+ yrs
Sex: All
Sponsor: Washington University School of Medicine
Primary completion: Jan 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Change From Baseline to 90-day Follow-up in Self Reported Weekly Minutes of Exercise	92.2; 37.5; 63.1; 60.0; 50.1; 49.3	0.0288 sig
PRIMARY Difference in Gist Comprehension of Risk Information by Risk Display Format	3.6; 3.4; 3.2	0.0333 sig
PRIMARY Difference in Verbatim Comprehension of Risk Information by Risk Communication Strategy	1.6; 1.6; 1.5	0.4946
PRIMARY Difference in Self-reported Intentions to Engage in Physical Activity by Risk Display Format	3.9; 4.0; 3.8	0.1397
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Maintenance Self-efficacy	2.95	0.0070 sig
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Recovery Self-efficacy	3.26	0.8793
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Affective Attitudes to Exercise - Enjoying Behavior	3.05	0.4673
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Affective Attitudes to Exercise - Thinking Behavior is Unpleasant	3.19	0.1916
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Perceived Vividness of Self-regulatory Imagery	3.36	0.8661
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Action Planning	3.52	0.0711
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Coping Planning	2.98	0.0365 sig
SECONDARY Effect of the Intervention on Physical Activity Levels as Measured by Action Self-efficacy	3.36	0.1511

Summary

Epidemiology seeks to improve public health by identifying risk factors for cancer and other diseases and conveying that information to relevant audiences (e.g., physicians, the public). The audience is presumed to understand and use that information to make appropriate decisions about lifestyle behaviors and medical treatments. Yet, even though a single risk factor can affect the risk of multiple health outcomes, this information is seldom communicated to people in a way that optimizes their understanding of the importance of engaging in a single healthy behavior. Providing individuals with the ability to understand how a single behavior (obtaining sufficient physical activity) could affect their risk of developing multiple diseases could foster a more coherent and meaningful picture of the behavior's importance in reducing health risks, increase motivation and intentions to engage in the behavior, and over time improve public health. The proposed study translates epidemiological data about five diseases that cause significant morbidity and mortality (i.e., colon cancer, breast cancer (women), heart disease, diabetes, and stroke) into a visual display that conveys individualized risk estimates in a comprehensible, meaningful, and useful way to diverse lay audiences.

Eligibility Criteria

Inclusion Criteria

30-64 years of age
Less than (3) relevant comorbidities (diabetes, heart disease, stroke, and cancer, where cancer counts as (2) comorbidities for women but (1) for men)
Having a SMS capable mobile phone that is not shared with anyone else

Exclusion Criteria

Not meeting national guidelines for aerobic physical activity (i.e., at least 150 minutes per week of moderate intensity aerobic physical activity)
Participants from HRPO# 201501028 will be ineligible for this study
Uses text messaging less than once per month

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03255291). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.