Phase 2 N=12 Randomized Prevention

Topical Treatment and Prevalence of P. Acnes

Surgical Site Infection

Bottom Line

View on ClinicalTrials.gov: NCT03257202 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2019

Primary outcome: Primary: Number of Subjects With Positive Bacterial Growth Culture Per Treatment Arms — 10; 12; 10; 10 participants

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: Clindamycin 1% Gel (Drug); Benzoyl peroxide 5% gel (Drug); BenzaClin 5%-1% Topical Gel (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Southern California
Primary completion: Jan 2018

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Subjects With Positive Bacterial Growth Culture Per Treatment Arms	10; 12; 10; 10	—

Summary

This study is about preventing surgical site infections of the shoulder. We hope to learn if clindamycin alone, benzoyl peroxide alone, or clindamycin and benzoyl peroxide together can affect growth of Propionibacterium acnes in the dermal layer.

Eligibility Criteria

Inclusion Criteria

healthy volunteer
age > 18

Exclusion Criteria

history of antibiotic use in the last month
active acne on the back
non-English speakers (the study personnel do not have adequate training to converse and consent in other languages)

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03257202). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.