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N/A N=20 Randomized Single-blind Treatment

Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites

Surgical Wound

Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Jul 2021
Primary outcome: Primary: Progression of Wound Healing — 69.9; 75.6 percentage of skin graft take

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
PICO Single Use Negative Pressure Wound Therapy System (Device); xeroform gauze (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Alabama at Birmingham
Primary completion
Apr 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Progression of Wound Healing
69.9; 75.6

Summary

Various management options for free flap donor sites that require split thickness skin grafting exist. None has proven superior from both a patient care and a cost standpoint. Major complications occurring at these surgical sites include wound breakdown, tendon exposure, and loss of function. We seek to investigate the use of the PICO single-use negative pressure wound therapy device in these surgical sites and determine if it can yield superior results to simpler methods.

Eligibility Criteria

Inclusion Criteria

  • > 18 years of age
  • participants are able to consent for themselves
  • undergoing reconstructive surgery requiring split-thickness skin graft coverage of a free flap donor site (i.e., radial forearm free flap or fibula free flap)

Exclusion Criteria

  • < 18 years of age
  • participants are unable to consent for themselves
  • undergoing reconstructive surgery that does not require split-thickness skin graft coverage of a free flap donor site
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03340025). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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