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Phase 3 N=185 Randomized Double-blind Treatment

Patient Narcotic Requirements After Outpatient Otolaryngology Procedures

Outpatient Surgery · Pain, Postoperative

Enrolled (actual)
185
Serious AEs
0.0%
Results posted
Mar 2022
Primary outcome: Primary: Narcotic Usage — 4.9; 2.0 Pills

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Norco (Drug); Ibuprofen (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Loma Linda University
Primary completion
Oct 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Narcotic Usage
4.9; 2.0
SECONDARY
Patient Pain Level
3.5; 2.8
SECONDARY
Ibuprofen Usage
4.5; 7.7

Summary

Patient's pain level and narcotic requirements will be evaluated after routine outpatient Otolaryngology procedures. This will be done by having study participants record their pain level and medication usage from home.

Eligibility Criteria

Inclusion Criteria

Patients undergoing one of the following outpatient procedure:

  • Septoplasty
  • Unilateral or Bilateral Functional endoscopic sinus surgery
  • Tympanomastoidectomy
  • Tympanoplasty
  • Total or Partial Thyroidectomy
  • Parathyroidectomy
  • Parotidectomy.
  • Age >18 years and 89 years
  • Post operative hospital admission
  • Allergy to Hydrocodone
  • Allergy or contraindication to Ibuprofen or NSAIDs
  • Pregnancy
  • Hepatic disease
  • Chronic kidney disease
  • Sickle cell anemia
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03404518). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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