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N/A Completed N=34 Randomized Double-blind Prevention

Effects of Fermented Vegetables on Gut Microflora and Inflammation in Women

Inflammation · Women's Health · Gastrointestinal Microbiome
Source: ClinicalTrials.gov NCT03407794 ↗
Enrolled (actual)
34
Serious AEs
0.0%
Results posted
Jan 2023
Primary outcomePrimary: C-reactive Protein — 160.7; 173.4; 211.4 ng/mL

Summary

This proposal will examine whether daily consumption of fermented vegetables for 6 weeks can impact the gut microflora and markers of inflammation of women between the ages of 18-70 years.

Outcome Measures

OutcomeResultp-value
PRIMARY
C-reactive Protein
160.7; 173.4; 211.4
PRIMARY
Shannon Index
3.14; 3.34; 3.38
SECONDARY
BMI
22.8; 23.3; 26.7
SECONDARY
Body Fat Percentage
31.1; 31.4; 36.8
SECONDARY
Systolic Blood Pressure
104; 121; 107
SECONDARY
Lipopolysaccharide
12.7; 12.7; 13

Eligibility Criteria

Inclusion Criteria

  • BMI: 18.5-40 kg/m2
  • Non-smoker
  • No previous diagnosis of cancer
  • No thyroid disease
  • No diabetes
  • Willing to consume 1/2 cup of vegetables daily for 6 weeks
  • No use of psychotic or depression medication
  • No medication to lose weight
  • Not on a weight loss diet
  • No use of antibiotics over the past 3 months
  • No consumption of fermented vegetables on a regular basis
  • No history of autoimmune disease, including gastrointestinal disease

Exclusion Criteria

  • BMI 40 kg/m2
  • Smoker
  • Taking medications that affect appetite or body weight
  • Uncontrolled Hypertension
  • Diabetes
  • Not willing to consume 1/2 cup of vegetables daily for 6 weeks
  • Willing to show up at two appointments
  • Following a fad diet
  • Using antibiotics frequently
  • Diagnosed with autoimmune disease, like psoriasis, rheumatoid arthritis, thyroid disease, colitis
  • Regular consumption of fermented vegetables
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03407794). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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