N/A
N=366
Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
Residual Neuromuscular Blockade · Residual Paralysis, Post-Anesthesia · Observational Study · Complication of Anesthesia · Neuromuscular Blockade
Bottom Line
View on ClinicalTrials.gov: NCT03417804 ↗Enrolled (actual)
366
Serious AEs
0.5%
Results posted
Jul 2021
Primary outcome: Primary: Percentage of Patients With Postoperative Residual Neuromuscular Blockade — 20 Participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Centro Hospitalar do Porto
- Primary completion
- Jul 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Patients With Postoperative Residual Neuromuscular Blockade |
20 | — |
| SECONDARY Percentage of Patients With Severe Residual Postoperative Neuromuscular Blockade |
2 | — |
| SECONDARY Association of Postoperative Residual Blockade and the Use of Reversal Agents |
— | — |
| SECONDARY Association of Postoperative Residual Blockade and the Use of Intra-operative Monitoring of Neuromuscular Blockade |
— | — |
Summary
This is an epidemiological multicenter, observational, prospective study, designed to determine the incidence of postoperative residual neuromuscular blockade - defined by a TOF (train-of-four) ratio < 0.9 - at PACU arrival.
Subjects aged at least 18 years old (n=360) admitted for different types of elective surgical procedures requiring general anesthesia with neuromuscular blocking agents will be included.
Eligibility Criteria
Inclusion Criteria
- 18 years of age or older;
- Informed consent signed;
- Admission for elective surgery;
- Administration of non-depolarizing NMBAs during surgery
Exclusion Criteria
- Admission for emergency surgery;
- Reoperation on the same hospital admission;
- More than 10 minutes elapsed between extubation and neuromuscular block monitoring at PACU
Data sourced from ClinicalTrials.gov (NCT03417804). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.