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N/A Completed N=63 Randomized Triple-blind Basic Science

Nutritional Therapy Interventions in Heart Failure

Heart Failure NYHA Class II
Source: ClinicalTrials.gov NCT03424265 ↗
Enrolled (actual)
63
Serious AEs
0.0%
Results posted
Aug 2020
Primary outcomePrimary: Functional Test — 115.91; 57.25 feet

Summary

The investigators will examine the effects of 12-weeks of nutritional interventions in older participants who have a symptom of mild to moderate heart failure.

Outcome Measures

OutcomeResultp-value
PRIMARY
Functional Test
115.91; 57.25

Eligibility Criteria

Inclusion Criteria

  • BMI between 18 and 40 kg/m2
  • Any ethnicity
  • Presence of mild-to-moderate heart failure (NYHA II or III symptomatology) as evidenced by prescribed diuretics or reported shortness of breath upon exertion

Exclusion Criteria

  • Allergic to milk or soy products
  • Hemoglobin <10 g/dL
  • Estimated Glomerular Filtration Rate (eGFR) < 30
  • Inability to perform strength and/or functional assessments
  • Myocardial infarction in the past 6 months
  • Unstable angina
  • Moderate-severe heart valve disease
  • Atrial fibrillation or other significant (as determined by PI) arrhythmias
  • Infiltrative, restrictive or hypertrophic cardiomyopathy
  • Dementia -determined by a SLUMS score of <20
  • Currently having inflammatory bowel disease
  • Received chemotherapy or radiation therapy within the past 12 months
  • Currently undergoing tube feeding
  • Currently receiving palliative care for end-of-life circumstance
  • Unwilling to refrain from using non-study protein/amino acid supplements during their participation in this study
  • If deemed medically unstable by the study physician for any other reason.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03424265). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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