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N/A N=24 Randomized Other

Evaluation of Post-Exposure Sauna Treatment of Firefighters - A Pilot Study

Post-fire Rehabilitation of Firefighters in Sauna

Enrolled (actual)
24
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcome: Primary: Urinary Excretion of Hydroxylated PAHs (PAH-OHs) — 10364.2; 40012.1; 6964.1; 22604.3 ng/L — p=0.0000009

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Sauna Rehabilitation (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Arizona
Primary completion
Jan 2020

Outcome Measures

OutcomeResultp-value
PRIMARY
Urinary Excretion of Hydroxylated PAHs (PAH-OHs)
10364.2; 40012.1; 6964.1; 22604.3 0.0000009 sig

Summary

Firefighters are at increased risk of cancer, and both inhalation and dermal routes contribute to overall exposure to carcinogens, including polycyclic aromatic hydrocarbons (PAHs). The purpose of the current study is to determine if post-fire firefighter rehabilitation in an infrared sauna: a) affects absorption of PAHs as measured by urinary metabolites; and b) changes core body temperature and heart rate.

Eligibility Criteria

Inclusion Criteria

  • Are employed as an active fire responder by the Fire Department
  • Are scheduled for a training fire exercise by the Fire Department in the next year
  • Are currently a non-smoker (including cigarettes, cigars and e-cigarettes)
  • Cannot have any contraindications to the core temp pill, which are:
  • weight less than 80 pounds
  • known or suspected obstructive disease of GI tract, including but not limited to diverticulitis and inflammatory bowel disease
  • exhibit or have a history of disorders or impairment of the gag reflex
  • have had a previous gastrointestinal surgery
  • have any diseases or disorders of the esophagus
  • will be undergoing Nuclear Magnetic Resonance (NMR) or MRI scanning less than 3 days after swallowing the sensor
  • have a low motility disorder of the gastrointestinal tract including but not limited to ileus
  • have a cardiac pacemaker or other implanted electromedical device
  • have a swallowing disorder

Exclusion Criteria

  • Are NOT employed as an active fire responder by the Fire Department
  • Are NOT scheduled for a training fire exercise by the Fire Department in the next year
  • Are currently a smoker (including cigarettes, cigars and e-cigarettes)
  • Has one of the contraindications to the core temp pill
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03429348). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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