N/A
N=216
Improving Communication During a Pandemic Flu Outbreak
Healthy
Bottom Line
View on ClinicalTrials.gov: NCT03431012 ↗Enrolled (actual)
216
Serious AEs
—
Results posted
Dec 2019
Primary outcome: Primary: Change in Intentions to Take Antivirals for Pandemic Flu — 8.29; 8.16; 8.23; 8.35 score on a scale — p=>.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Agency Assignment framing (Other); Attribute framing (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- King's College London
- Primary completion
- Jun 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Intentions to Take Antivirals for Pandemic Flu |
8.29; 8.16; 8.23; 8.35 | >.05 |
| SECONDARY Worry of the Pandemic Flu Threat |
6.06; 6.50 | =.113 |
| SECONDARY Perceived Susceptibility to the Pandemic Flu |
6.32; 6.37 | =.809 |
| SECONDARY Perceived Severity of the Pandemic |
5.92; 6.59 | 0.025 sig |
| SECONDARY Perceived Self-efficacy |
8.23; 8.45 | =0.199 |
| SECONDARY Perceived Efficacy of the Antivirals |
6.45; 6.59 | =0.484 |
| SECONDARY Perceived Response Costs |
3.53; 3.70 | =0.494 |
Summary
During the last pandemic influenza antivirals were prescribed both as prophylaxis and treatment. However, adherence rates were suboptimal. This study assessed the effect of theory-based and evidence-based health messages, which promoted the use of antivirals as prophylaxis for pandemic influenza, on intentions to use antivirals. Using hypothetical scenarios, the investigators tested whether written health communications about pandemic flu and recommended preventative medication (i.e. a prophylactic treatment with antivirals) had an effect on study participants' beliefs about the pandemic flu and the advice received, and their intention to adhere to the recommendation. In particular, the investigators assessed the behavioural impact of health messages presented in four different linguistic formats, defined by a 2×2 (agency assignment × attribute framing) factorial design. The originality of this study relies on the attempt to maximise the behavioural impact of written health messages by combining the agency assignment and attribute framings, which have never been tested together, and by systematically targeting specific predictors of adherence intentions through these messages. The findings of this study may be used to improve the behavioural impact of health communications to the general public in case of a pandemic flu outbreak in the UK.
Eligibility Criteria
Inclusion Criteria
- To be eligible to participate, respondents had to be members of the UK general public in the adult age range (18-65 years), and be fluent in English.
Exclusion Criteria
- non-UK residents
- younger than 18 or older than 65
- not fluent in English
Data sourced from ClinicalTrials.gov (NCT03431012). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.