Mode
Text Size
Log in / Sign up
N/A N=216 Randomized Single-blind Prevention

Improving Communication During a Pandemic Flu Outbreak

Healthy

Enrolled (actual)
216
Serious AEs
Results posted
Dec 2019
Primary outcome: Primary: Change in Intentions to Take Antivirals for Pandemic Flu — 8.29; 8.16; 8.23; 8.35 score on a scale — p=>.05

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Agency Assignment framing (Other); Attribute framing (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
King's College London
Primary completion
Jun 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Intentions to Take Antivirals for Pandemic Flu
8.29; 8.16; 8.23; 8.35 >.05
SECONDARY
Worry of the Pandemic Flu Threat
6.06; 6.50 =.113
SECONDARY
Perceived Susceptibility to the Pandemic Flu
6.32; 6.37 =.809
SECONDARY
Perceived Severity of the Pandemic
5.92; 6.59 0.025 sig
SECONDARY
Perceived Self-efficacy
8.23; 8.45 =0.199
SECONDARY
Perceived Efficacy of the Antivirals
6.45; 6.59 =0.484
SECONDARY
Perceived Response Costs
3.53; 3.70 =0.494

Summary

During the last pandemic influenza antivirals were prescribed both as prophylaxis and treatment. However, adherence rates were suboptimal. This study assessed the effect of theory-based and evidence-based health messages, which promoted the use of antivirals as prophylaxis for pandemic influenza, on intentions to use antivirals. Using hypothetical scenarios, the investigators tested whether written health communications about pandemic flu and recommended preventative medication (i.e. a prophylactic treatment with antivirals) had an effect on study participants' beliefs about the pandemic flu and the advice received, and their intention to adhere to the recommendation. In particular, the investigators assessed the behavioural impact of health messages presented in four different linguistic formats, defined by a 2×2 (agency assignment × attribute framing) factorial design. The originality of this study relies on the attempt to maximise the behavioural impact of written health messages by combining the agency assignment and attribute framings, which have never been tested together, and by systematically targeting specific predictors of adherence intentions through these messages. The findings of this study may be used to improve the behavioural impact of health communications to the general public in case of a pandemic flu outbreak in the UK.

Eligibility Criteria

Inclusion Criteria

  • To be eligible to participate, respondents had to be members of the UK general public in the adult age range (18-65 years), and be fluent in English.

Exclusion Criteria

  • non-UK residents
  • younger than 18 or older than 65
  • not fluent in English
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03431012). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search