Phase 3
Completed N=96
Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy
Hip Disease
Source: ClinicalTrials.gov NCT03432650 ↗
Enrolled (actual)
96
Serious AEs
0.0%
Results posted
Aug 2022
Primary outcomePrimary: Numerical Pain Rating System (NRS) Pain Scores — 3.3; 4.4; 4.5; 4.7 score on a scale
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
Hip arthroscopy is performed frequently and the postoperative course often involves moderate to severe pain. There remains no definitive perioperative pain regimen that has been proven to be effective and safe for this ambulatory procedure. Some institutions perform peripheral nerve blocks either preoperatively or postoperatively as a rescue block. All of these PNBs lead to quadriceps weakness which may impede earlier mobilization and physical therapy. While some case reports exist, there have not been any studies evaluating the QLB for hip arthroscopy patients. As previously mentioned, the technique is easy to perform, well-tolerated by patients, and avoids side effects such as hypotension, urinary retention, or the quadriceps weakness associated with lumbar plexus blockade.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Numerical Pain Rating System (NRS) Pain Scores |
3.3; 3.8; 5.7; 5.7 | — |
| SECONDARY Opioid Use |
75; 68 | — |
| SECONDARY Number of Patients With Presence of IAFE (Intraabdominal Fluid Extravasation) Following Surgery |
9; 11 | — |
| SECONDARY Number of Patients With Nausea/Vomiting |
12; 7; 21; 19; 0; 1 | — |
| SECONDARY Antiemetic Use |
18; 12 | — |
| SECONDARY Number of Participants With Hospital Admission |
11; 9 | — |
| SECONDARY Patient Satisfaction With Post Op Pain Control |
8; 9; 8; 9 | — |
| SECONDARY Patient Score on Quality of Recovery-40 (QoR40) Inventory. |
104.9; 107.5; 105.6; 105 | — |
| SECONDARY Change in Quadriceps Motor Strength on Surgical Side |
-4.4; -3.5 | — |
| SECONDARY Urinary Retention |
1; 0 | — |
| SECONDARY Incidence of Hypotension |
16; 19 | — |
Eligibility Criteria
Inclusion Criteria
- Patients scheduled for hip arthroscopy
- Ability to follow study protocol
- English Speaking
Exclusion Criteria
- Hepatic or renal insufficiency
- Younger than 18 years old and older than 80
- Allergy or intolerance to one of the study medications
- Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
- Chronic opioid use (daily opioids use for longer than 3 months)
- Patients contraindicated to undergo a spinal anesthetic
- Non English Speakers
Data sourced from ClinicalTrials.gov (NCT03432650). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.