N/A
N=98
Pilot Intervention to Empower HIV Clients as Prevention Advocates in Uganda
HIV
Bottom Line
View on ClinicalTrials.gov: NCT03435497 ↗Enrolled (actual)
98
Serious AEs
0.0%
Results posted
Jun 2020
Primary outcome: Primary: Change in Engagement HIV Prevention Advocacy — 4.1; 3.8; 4.2; 3.5 units on a scale — p=.017
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Game Changers (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- RAND
- Primary completion
- Jul 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Engagement HIV Prevention Advocacy |
4.1; 3.8; 4.2; 3.5; 4.0; 3.6 | .017 sig |
| SECONDARY Change in Sexual Risk Behavior Among Alters |
13; 14; 16; 12 | .05 |
| SECONDARY Change in HIV Treatment Adherence |
.91; .93; .92; .93; .95; .93 | 0.48 |
| SECONDARY Change in Internalized HIV Stigma |
1.7; 1.8; 1.6; 1.9; 1.4; 1.7 | 0.012 sig |
| SECONDARY Number of Participants Who Have Reported Their HIV Status to Their Main Partner |
31; 30; 29; 28; 31; 27 | 0.022 sig |
Summary
This randomized controlled pilot study of the "Game Changers" program will:
1. Assess the feasibility and acceptability of implementing an HIV prevention advocacy intervention with people living with HIV who are in HIV care, and who will be trained to be advocates of HIV protective behaviors within their social networks.
2. Assess preliminary intervention effects on a) protective behavior of the HIV-positive clients (condom use, partner concurrency/number of partners, engagement in HIV care, ART adherence); and b) diffusion of prevention messages across the network, as assessed by the content and extent of communication with network members about protective behaviors (condom use, partner concurrency/number of partners, HIV testing, engagement in HIV care, circumcision), HIV disclosure, and HIV stigma.
3. Explore characteristics of HIV-positive clients who more effectively engage in prevention advocacy (in terms of socio-demographics, network characteristics, and network position and type of alters receiving advocacy).
Eligibility Criteria
Inclusion Criteria (People living with HIV):
- 18+ years old
- In HIV care for > 1 year
- Having disclosed serostatus to at least one person
Inclusion Criteria (Social network members):
- 18+ years old
- Referred by a patient participant because they are family members, friends, or other people in patients' social network
- knows patient participant's serostatus
Exclusion Criteria
- Individuals who meet the inclusion criteria above will be eligible to participate, and no other exclusion criteria apply.
Data sourced from ClinicalTrials.gov (NCT03435497). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.