N/A
Completed N=46
Computer Training and Transcranial Direct Current Stimulation for Cognition in HIV
HIV-related Mild Neurocognitive Disorder
Source: ClinicalTrials.gov NCT03440840 ↗
Enrolled (actual)
46
Serious AEs
0.0%
Results posted
Sep 2023
Primary outcomePrimary: Psychomotor Speed — 54.2; 60.4; 53.4 score on a scale — p=0.40
Summary
This study investigates the effectiveness of computer-based cognitive training with or without transcranial direct current stimulation (tDCS) in improving the functioning of older individuals with HIV-related cognitive dysfunction.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Psychomotor Speed |
54.2; 60.4; 53.4 | 0.40 |
| SECONDARY Functional Status |
84.6; 82.8; 84.4 | 0.37 |
| SECONDARY Participant Assessment of Own Functioning (PAOF) |
7.98; 7.73; 7.86 | 0.37 |
| SECONDARY Center for Epidemiological Studies Depression Scale (CES-D) |
16.5; 16.6; 16.3 | 0.61 |
Eligibility Criteria
Inclusion Criteria
- Treated with antiretroviral medication for at least one month
- Meet criteria for Mild Neurocognitive Disorder
Exclusion Criteria
- Seizure disorder
- Recent head injury or surgery
- Personal or family history of bipolar disorder;
- Some medications
- Left handedness
- HIV Dementia
Data sourced from ClinicalTrials.gov (NCT03440840). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.