N/A
Completed N=428
Impacts of Inspection During Instrument Insertion on Colonoscopy Quality
Colon Polyp · Colon Adenoma
Source: ClinicalTrials.gov NCT03444090 ↗
Enrolled (actual)
428
Serious AEs
0.0%
Results posted
May 2019
Primary outcomePrimary: Percentage of Participants With Detection of at Least One Adenoma Per Procedure — 63.7; 68.1 percentage of participants
Summary
Small colon polyps which are found during colonoscopy insertion are sometimes difficult to find during withdrawal and thus missed. The investigators aim to evaluate the differences of colon polyp/adenoma detection rates of patients undergoing additional inspection and polypectomy during insertion as compared to the patients undergoing traditional practice of careful inspection and polypectomy performed entirely during withdrawal of colonoscopy.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Participants With Detection of at Least One Adenoma Per Procedure |
63.7; 68.1 | — |
| SECONDARY Mean Colon Adenoma Per Colonoscopy |
1.6; 1.9 | — |
Eligibility Criteria
Inclusion Criteria
- Aged 45 years or older.
- Agree to participate the study and provide a written informed consent
Exclusion Criteria
- Previous surgical resection of the colon or rectum
- Inflammatory bowel disease
- Polyposis syndrome
- Previously incomplete colonoscopy
- Obstructive lesions of colon
- Inadequate bowel preparation, defined as Boston Bowel Preparation Scale score of 0 or 1 in any colon segment
- Gastrointestinal bleeding
- Allergy to fentanyl or midazolam
- American Society of Anesthesiology classification of physical status 3 or higher
- Mental retardation
- Pregnancy
- Refusal to provide a written informed consent
Data sourced from ClinicalTrials.gov (NCT03444090). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.