Phase 2 N=31 Randomized Single-blind Treatment

Capnometry-Assisted Breathing Training for COPD

Chronic Obstructive Pulmonary Disease

Bottom Line

View on ClinicalTrials.gov: NCT03457103 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2021

Primary outcome: Primary: Number of Participants With Adherence to Home Breathing Exercises — 10; 5 Participants

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: Capnometry-Assisted Training for COPD to Slow the Breath (CATCH) (Device); Pulmonary Rehabilitation (PR) (Device)
Age: Adult, Older Adult · 40+ yrs
Sex: All
Sponsor: NYU Langone Health
Primary completion: Aug 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Number of Participants With Adherence to Home Breathing Exercises	10; 5	—
SECONDARY Difference in Mean 6MWT Distance Between Pre and Post Intervention	39.37; 24.99	—
SECONDARY Difference in Mean Dyspnea Management Questionnaire Computer Adaptive Test (DMQ-CAT) Anxiety Score Between Pre and Post Intervention	2.43; -3.16	—
SECONDARY Mean Difference in Heart Rate Maximum Between Pre and Post Intervention	6.2; 3	—
SECONDARY Difference in Mean PROMIS Fatigue Score Between Pre and Post Intervention	-4.18; 5.2	—
SECONDARY Mean Difference in Resting Respiratory Rate Between Pre and Post Intervention	-2.75; -4.2	—
SECONDARY Difference in Mean Score on St George's Respiratory Questionnaire (SGRQ) Between Pre and Post Intervention	-11.76; -9.96	—

Summary

Capnometry-Assisted Breathing Training for COPD (CATCH) is a behavioral intervention that aims to promote optimal, self-regulated, mindful breathing. A portable capnometer is used in-session to provide continuous visual feedback of Respiratory Rate (RR), End-Tidal Carbon Dioxide Tension (ETCO2), and breathing pattern. The tailored CATCH intervention will emphasize a slow, quiet, regular, nasal breathing pattern, as well as pursed lips breathing (PLB). CATCH is once weekly for 6 weeks, for a total of 6 sessions; each session is approximately 60 minutes long. The principal investigator will implement the CATCH intervention. The principal investigator will implement the CATCH intervention. Patients will use the Address Stress app on a smart phone or computer tablet as part of their home breathing exercises.

Eligibility Criteria

Inclusion Criteria

over 40 years of age
has COPD documented in their electronic medical record, as defined by FEV1/FVC of 40)
Is currently smoking
Has unstable cardiac disease defined by a history of a myocardial infarction in the past 3 months

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03457103). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.