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N/A N=2,554 Randomized Single-blind Prevention

Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination

Papillomavirus Vaccines

Enrolled (actual)
2,554
Serious AEs
Results posted
Oct 2024
Primary outcome: Primary: Human Papillomavirus or HPV-vaccine-dose Receipt — 782; 578; 408; 1056 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Current care (Behavioral); Reminder-recall (Behavioral); Audit-and-feedback (Behavioral); Combined reminder-recall and audit-and-feedback (Behavioral)
Age
Pediatric · 11+ yrs
Sex
All
Sponsor
Mayo Clinic
Primary completion
Aug 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Human Papillomavirus or HPV-vaccine-dose Receipt
782; 578; 408; 1056
SECONDARY
Initiation
482; 329; 251; 490
SECONDARY
Completion
300; 249; 157; 566

Summary

Each year the human papillomavirus (HPV) causes 30,000 cancers in the United States despite the availability of very effective and safe vaccines. Uptake of the HPV vaccine has been disappointingly low and lags behind other adolescent vaccines. This study seeks to test interventions targeting health care system, provider, and patient factors to improve the population uptake of the HPV vaccine.

Eligibility Criteria

Inclusion Criteria

  • Empaneled in one of the six participating primary care practices
  • 11 to 12 years of age at the first day of each of the 12-month-long steps
  • Due during that 12-month-long step for at least one dose of the HPV vaccine

Exclusion Criteria

  • Not empaneled in one of the six participating practices
  • Empaneled in one of the six participating practices but less than 11 years of age or more than 12 years of age on the first day of each 12 month long step
  • Not due during that 12-month-long step for a dose of HPV vaccine.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03501992). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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