N/A
N=187
Effects Among Smokers Who Use and Do Not Use E-Cigarettes
Toxicant Exposure
Bottom Line
View on ClinicalTrials.gov: NCT03511001 ↗Enrolled (actual)
187
Serious AEs
0.0%
Results posted
Sep 2021
Primary outcome: Primary: Toxicant Exposure — 40; 97 pg/ml
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- E-Cigarette Vs. Smoking as Usual (Other)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- California State University, San Marcos
- Primary completion
- May 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Toxicant Exposure |
40; 97 | — |
| SECONDARY Carbon Monoxide |
7; 16 | — |
| SECONDARY Respiratory Symptoms |
7; 9 | — |
| SECONDARY Lung Function |
2.8; 2.7 | — |
| SECONDARY Systolic Blood Pressure |
128; 133 | — |
| SECONDARY Diastolic Blood Pressure |
83; 83 | — |
| SECONDARY Tobacco Dependence |
18.5; 41.0 | — |
| SECONDARY Self-efficacy to Resist Smoking |
43.0; 20.0 | — |
Summary
This study compares effects among Latino and African American cigarette smokers who use e-cigarettes with those who continue smoking as usual.
Eligibility Criteria
Inclusion Criteria
- > 21 years of age
- Smoked cigarettes on > 25 of past 30 days
- Smoked > 5 cigarettes per day on days smoked
- Smoked cigarettes > 6 months
- Carbon monoxide > 5 PPM at baseline
- Hispanic/Latino or African American/Black
- Fluent in English or Spanish
- Willing to switch from smoking cigarettes to ECs for 6 weeks
- Regular access to telephone
- Transportation to attend appointments (KC Only)
Exclusion Criteria
- Primary use of other tobacco products or equal use of cigarettes and other tobacco products
- Electronic cigarette use on > 4 of the past 30 days
- Currently in a smoking cessation program or another clinical trial
- Use of nicotine replacement therapy or medication which aids smoking cessation in the past 30 days
- Hospitalization for a psychiatric issue in the past 30 days
- Heart-related event in the past 30 days. Examples include heart attack, stroke, severe angina (i.e. chest pain), ischemic heart disease, and vascular disease
- Uncontrolled blood pressure at baseline
- Planning to move out of San Diego or Kansas City in the next 6 weeks
- Another person in the household enrolled in the study
- Women: pregnant, breastfeeding, or planning to become pregnant in the next six months
- Unstable mental status or health status
Data sourced from ClinicalTrials.gov (NCT03511001). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.