Phase 2
N=133
Behavioral Economic Analysis of Demand for Marijuana
Marijuana Smoking
Bottom Line
View on ClinicalTrials.gov: NCT03518567 ↗Enrolled (actual)
133
Serious AEs
0.0%
Results posted
Feb 2024
Primary outcome: Primary: Validity of the Marijuana Purchase Task (MPT) — 63 percentage of participants — p=.00000004
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- Smoked marijuana cigarettes: High THC dose (6% THC) (Drug)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Brown University
- Primary completion
- May 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Validity of the Marijuana Purchase Task (MPT) |
63 | .00000004 sig |
| SECONDARY Change in Marijuana Craving Questionnaire (MCQ) |
-0.75 | .000000009 sig |
| SECONDARY Marijuana Smoking Topography |
29 | .87 |
Summary
This laboratory study will employ a multi-session experimental design to examine the behavioral economic demand for marijuana, by studying effect of marijuana administration (High THC) on demand for marijuana, and marijuana smoking topography. The study will recruit 100 non-treatment seeking marijuana users who smoke marijuana at least twice weekly.
Eligibility Criteria
Inclusion Criteria
- marijuana use at least 8 times in the past month on average and at least monthly for the past 6 months
- English-speaking
- negative urine toxicology screen for drugs other than marijuana
- non-treatment seeking
- purchase of marijuana at least twice in the past 6 months to confirm familiarity with the construct to be measured
Exclusion Criteria
- positive pregnancy test
- nursing
- inability to use contraception during the study
- poor physical health
- positive breath alcohol concentration
- diagnosis of a current affective disorder, psychosis, and panic disorder
- self-report of past serious adverse reaction to marijuana
- current psychotropic drug use
- smoking more than 20 tobacco cigarettes per day
- inability to abstain from marijuana for 15 hours
- body mass index outside 18.5-30 kg/m2 range
Data sourced from ClinicalTrials.gov (NCT03518567). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.