Phase 4
Completed N=428
Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation
Intubation Complication
Source: ClinicalTrials.gov NCT03545503 ↗
Enrolled (actual)
428
Serious AEs
0.3%
Results posted
Nov 2021
Primary outcomePrimary: Hemodynamic Effect as Measured by Systolic Blood Pressure Before and After RSI — 138.04; 132.39; 139.09; 130.09 mmHg
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
The purpose of this study is to compare the hemodynamic effects of ketamine v etomidate during rapid sequence intubation (RSI) in the pre-hospital and emergency department setting.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Hemodynamic Effect as Measured by Systolic Blood Pressure Before and After RSI |
138.04; 132.39; 139.09; 130.09; 130.42; 120.80 | — |
Eligibility Criteria
Inclusion Criteria
- Persons greater than 18yrs requiring rapid sequence intubation for any reason.
Exclusion Criteria
- Pregnant patients
- Children under the age of 18
- Patients with a known hypersensitivity to etomidate or ketamine
Data sourced from ClinicalTrials.gov (NCT03545503). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.