N/A
N=108
Association Between Food/Nutrient Intake and Sleep Quality in Middle Aged and Older Population
Sleep
Bottom Line
View on ClinicalTrials.gov: NCT03554954 ↗Enrolled (actual)
108
Serious AEs
0.0%
Results posted
Jun 2020
Primary outcome: Primary: Sleep Quality Assessment 1 (GSS) — 3.4; 8.1; 5.2 score on a scale
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Adult, Older Adult · 50+ yrs
- Sex
- All
- Sponsor
- National University of Singapore
- Primary completion
- Oct 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sleep Quality Assessment 1 (GSS) |
3.4; 8.1; 5.2 | — |
| PRIMARY Sleep Quality Assessment 2 |
5.54; 9.08; 6.87 | — |
| PRIMARY Dietary Assessment |
— | — |
| PRIMARY Dietary Assessment 2 (Dietary Carotenoids) |
11.6; 8.8; 10.5 | — |
| PRIMARY Blood Amino Acid Concentration (Plasma Tryptophan) |
21.6; 24.7; 22.8 | — |
| PRIMARY Dietary Assessment 2 (Dietary Macronutrients) |
34.3; 32.8; 33.7; 47.3; 48.1; 47.6 | — |
| PRIMARY Sleep Quality Assessment 1 (Sleep Duration) |
6.7; 6.2; 6.5 | — |
| PRIMARY Sleep Quality Assessment 1 (Sleep Latency) |
10; 26; 16.0 | — |
| PRIMARY Sleep Quality Assessment 1 (Sleep Efficiency) |
93.9; 84.6; 90.4 | — |
| SECONDARY Blood Pressure |
118.9; 113.4; 116.8; 76; 73.1; 74.9 | — |
| SECONDARY Anthropometric Measurements 1 |
161.9; 160.2; 161.3 | — |
| SECONDARY Anthropometric Measurements 2 |
63.2; 60.7; 62.3 | — |
| SECONDARY Anthropometric Measurements 3 |
83.6; 81.5; 82.8 | — |
| SECONDARY Skin Carotenoid Status |
32746; 35307; 33707 | — |
| SECONDARY Perceived Stress Assessment |
10.5; 14.8; 12.1 | — |
| SECONDARY Blood Lipid and Glucose Profile |
1.23; 1.16; 1.20; 5.4; 5.3; 5.3 | — |
| SECONDARY Plasma Carotenoids Concentration |
1.14; 1.22; 1.17 | — |
Summary
Sleep is essential to health. Quality of sleep, measure through indexes of sleep, is related to the incidence of obesity, type 2 diabetes, cardiovascular disease, hypertension, and premature death. Sleep pattern changes as people age. They tend to have a harder time falling asleep and more trouble staying asleep than when they were younger. Studies have shown that food/nutrient intake may be associated with sleep duration, quality, and patterns. Singapore's population is aging rapidly and improving their indexes of sleep may result in their health promotion.
Eligibility Criteria
Inclusion Criteria
- Ability to give an informed consent
- Age 50 to 75 years
- Not taking dietary supplements which may impact the outcome of the interests (I.e. dietary protein and vitamin supplements)
- Not having significant dietary changes for the past 1 year (i.e. weight loss, vegetarian diet)
- Having sufficient venous access to allow the blood collection
- Willing to follow the study procedure
Exclusion Criteria
- Unable to give an informed consent
- Age < 50 years
- Taking dietary supplements which may impact the outcome of the interest (i.e. dietary proteins and vitamin supplements)
- Having/had significant dietary changes for the past 1 year
- Not having sufficient venous access to allow the blood collection
- Unwilling to follow the study procedure
Data sourced from ClinicalTrials.gov (NCT03554954). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.