N/A
N=35
The Effect of Acute Mild Dehydration on Blood Pressure Control
Mild Dehydration
Bottom Line
View on ClinicalTrials.gov: NCT03560869 ↗Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcome: Primary: Blood Pressure Variability — 2.6; 2.5 mmHg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Normal hydration (Other); Dehydration (Other)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- University of Delaware
- Primary completion
- Jun 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Blood Pressure Variability |
2.6; 2.5 | — |
| PRIMARY Blood Pressure Reactivity - Handgrip Exercise |
20; 18 | — |
Summary
The goal of this project is determine how acute mild dehydration impacts blood pressure control at rest and during static exercise. This protocol will test healthy young and older adults in a normally hydrated and dehydrated condition.
Eligibility Criteria
Inclusion Criteria (Young):
- age: 20-35 years old
Exclusion Criteria (Young):
- high blood pressure (>140/90 mmHg)
- history of cardiovascular disease
- history of cancer
- history of diabetes
- history of kidney disease
- obesity (BMI > 30 kg/m2)
- smoking or tobacco use
- current pregnancy
- nursing mothers
- communication barriers
Inclusion Criteria (Older):
- age: 60-75 years old
- ECG within normal limits
- screening blood panel within normal limits
Exclusion Criteria (Older):
- high blood pressure (>140/90 mmHg)
- history of cardiovascular disease
- history of cancer
- history of diabetes
- history of kidney disease
- obesity (BMI > 30 kg/m2)
- smoking or tobacco use
- current pregnancy
- nursing mothers
- communication barriers
Data sourced from ClinicalTrials.gov (NCT03560869). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.