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N/A Completed N=35 Randomized Single-blind Basic Science

The Effect of Acute Mild Dehydration on Blood Pressure Control

Mild Dehydration
Source: ClinicalTrials.gov NCT03560869 ↗
Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcomePrimary: Blood Pressure Variability — 2.6; 2.5 mmHg

Summary

The goal of this project is determine how acute mild dehydration impacts blood pressure control at rest and during static exercise. This protocol will test healthy young and older adults in a normally hydrated and dehydrated condition.

Outcome Measures

OutcomeResultp-value
PRIMARY
Blood Pressure Variability
2.6; 2.5
PRIMARY
Blood Pressure Reactivity - Handgrip Exercise
20; 18

Eligibility Criteria

Inclusion Criteria (Young):

  • age: 20-35 years old

Exclusion Criteria (Young):

  • high blood pressure (>140/90 mmHg)
  • history of cardiovascular disease
  • history of cancer
  • history of diabetes
  • history of kidney disease
  • obesity (BMI > 30 kg/m2)
  • smoking or tobacco use
  • current pregnancy
  • nursing mothers
  • communication barriers

Inclusion Criteria (Older):

  • age: 60-75 years old
  • ECG within normal limits
  • screening blood panel within normal limits

Exclusion Criteria (Older):

  • high blood pressure (>140/90 mmHg)
  • history of cardiovascular disease
  • history of cancer
  • history of diabetes
  • history of kidney disease
  • obesity (BMI > 30 kg/m2)
  • smoking or tobacco use
  • current pregnancy
  • nursing mothers
  • communication barriers
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03560869). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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