The Diet Gout Trial
Gout · Hyperuricemia
Bottom Line
View on ClinicalTrials.gov: NCT03569020 ↗Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Subsidy for food purchases and dietitian education (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins University
- Primary completion
- Jul 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Uric Acid Level |
7.75; 7.98 | — |
| PRIMARY Uric Acid Level |
7.75; 7.98 | — |
| PRIMARY Uric Acid Level |
7.75; 7.98 | — |
| SECONDARY Systolic Blood Pressure (mm Hg) |
125.0; 123.5; 126.4; 123.7; 129.4; 124.8 | — |
| SECONDARY Diastolic Blood Pressure (mm Hg) |
74.9; 72.6; 76.1; 75.0; 77.3; 74.0 | — |
| SECONDARY Fasting Blood Glucose (mg/dL) |
93.0; 103.0; 96.5; 103.2; 97.1; 97.6 | — |
| SECONDARY Low Density Lipoprotein Cholesterol (mg/dL) |
109.0; 115.5; 105.3; 113.4; 107.5; 105.5 | — |
| SECONDARY Body Mass Index (kg/m^2) |
33.4; 33.5; 33.0; 33.6; 33.6; 33.5 | — |
Summary
Eligibility Criteria
Inclusion Criteria
Age > 18-100 years
Self-reported gout diagnosis
Serum Uric Acid > 7 mg/dL
Exclusion Criteria
Recent or planned changes to urate lowering therapies (e.g. allopurinol, febuxostat, probenecid)
Recent or planned changes to hypertension, lipid, or diabetes medications
Patients with hyperkalemia (>5 mmol/L)
Chronic kidney disease (GFR < 30 cc/min), kidney transplant, dialysis
Gastro-intestinal conditions (e.g. history of gastric bypass surgery, active inflammatory bowel disease, malabsorption, or major GI resection)
Active cancer treatment (e.g. radiation or chemotherapy)
Diagnosis of any of the following in the past 6 months: heart attack, heart failure, angina, coronary bypass or angioplasty, or Chronic Obstructive Pulmonary Disease (COPD)
Alcohol use over 14 drinks per week
Inability to give informed consent
Active use of warfarin, insulin, or chronic steroids (like prednisone)
Terminal or mental illness
Data sourced from ClinicalTrials.gov (NCT03569020). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.