N/A N=74 Randomized Double-blind Prevention

Moderate vs Deep Neuromuscular Block on Biotrauma During Laparoscopy

Pneumoperitoneum

Bottom Line

View on ClinicalTrials.gov: NCT03576118 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2020

Primary outcome: Primary: Change of Cytokine — 35.9; 12.2; 31.4; 22.9 pg/ml

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Deep neuromuscular block (Drug); Moderate neuromuscular block (Drug)
Age: Adult, Older Adult · 25+ yrs
Sex: All
Sponsor: Ajou University School of Medicine
Primary completion: Jul 2019

Outcome Measures

Outcome	Result	p-value
PRIMARY Change of Cytokine	35.9; 12.2; 31.4; 22.9; 41.53; 32.9	—

Summary

The purposes of this study is to investigate the effects of moderate vs. deep neuromuscular block on respiratory mechanics and biotrauma in patients with intraoperative protective lung ventilation for laparoscopy.

Eligibility Criteria

Inclusion Criteria

ASA physical status I or II, aged 25 to 80 years, scheduled for laparoscopic surgery with trendelenburg position

Exclusion Criteria

cerebrovascular disease
uncontrolled hypertension, asthma, COPD
neuromuscular disorder
patients who have had abdominal surgery
morbid obesity (body mass index > 35 kg/m2)

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Data sourced from ClinicalTrials.gov (NCT03576118). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.