Phase 1
N=82
Effects of RLIC on Motor Learning in Middle-aged and Older Adults
Adults · Older Adults
Bottom Line
View on ClinicalTrials.gov: NCT03582943 ↗Enrolled (actual)
82
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcome: Primary: Change in Balance Score — 5.55; 4.81 seconds — p=0.984
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 1
- Interventions
- RLIC (Behavioral); Sham conditioning (Behavioral); Balance training (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- Washington University School of Medicine
- Primary completion
- Sep 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Balance Score |
5.55; 4.81 | 0.984 |
Summary
The purpose of this research is to determine if the beneficial effects of remote limb ischemic conditioning on learning seen in young adults are found in middle-aged and older adults.
Eligibility Criteria
Inclusion Criteria
- 40-80 years old
- Had sufficient cognitive skills to provide informed consent and actively participate.
Exclusion Criteria (determined by self-report):
- History of a neurological condition, balance impairment, or vestibular disorder.
- History of attentional disorders (ADD/ADHD) that could affect learning.
- History of sleep apnea which could confound the effects of RLIC.
- Presence of lower extremity condition, injury, or surgery that would compromise performance on the balance task.
- Learning disability, sensory, or communication problem that would prevent completion of the study.
- History of epilepsy, peripheral vascular disease, or blood diathesis which could contraindicate RLIC.
- Current intensive weight lifting or interval training exercise which could confound the effects of RLIC.
- Current substance abuse or dependence.
Data sourced from ClinicalTrials.gov (NCT03582943). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.