N/A
Completed N=139
Standing Cognition and Co-morbidities of POTS Evaluation
Postural Tachycardia Syndrome · Ehlers-Danlos Syndrome
Source: ClinicalTrials.gov NCT03602482 ↗
Enrolled (actual)
139
Serious AEs
0.0%
Results posted
Apr 2021
Primary outcomePrimary: Executive Function (Stroop Word-color Test) — 48; 49; 50; 58 Testing Scores
Summary
The purpose of this study is to evaluate cognition in patients with postural tachycardia syndrome (POTS) while lying down and standing and to assess the prevalence of hypermobile Ehlers-Danlos Syndrome in POTS.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Executive Function (Stroop Word-color Test) |
48; 49; 50; 58; 45; 54 | — |
| SECONDARY Attention Score Using Cogstate Identification Task |
2.78; 2.78; 2.70; 2.68; 2.74; 2.64 | — |
| SECONDARY Number of Participants With Hypermobile Ehlers-Danlos Syndrome (hEDS) |
28 | — |
| SECONDARY Heart Rate Standing Minus Heart Rate Supine |
15; 12 | — |
Eligibility Criteria
Inclusion Criteria
- Previously diagnosed with POTS, or healthy control
- Age between 13-60 years
- Participants may be any race, ethnicity, sex, or gender
- Able and willing to provide informed consent
Exclusion Criteria
- Inability to give, or withdrawal of, informed consent
- Age ≤ 13 or ≥ 61 years
- Prisoners
- Unable to stand
Data sourced from ClinicalTrials.gov (NCT03602482). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.