N/A
Completed N=11
Acute Effects of Watermelon on Vascular Function and Serum Lycopene
Vascular Health of Postmenopausal Women
Source: ClinicalTrials.gov NCT03608254 ↗
Enrolled (actual)
11
Serious AEs
0.0%
Results posted
Mar 2022
Primary outcomePrimary: Change From Baseline in Circulating Lycopene Levels — 2.85 umol/L
Summary
This study aimed to examine the effects of a one-time dose of 100% watermelon juice on circulating lycopene levels and measures of vascular health among a cohort of postmenopausal women.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change From Baseline in Circulating Lycopene Levels |
2.85 | — |
| SECONDARY Change From Baseline in Endothelial-dependent Vasodilation |
2.33 | — |
Eligibility Criteria
Inclusion Criteria
- Body mass index 18.5 - 29.9 kg/m2 (non-obese)
- Ambulatory
- Postmenopausal female
- Ages 65-70 years
Exclusion Criteria
- Food allergy to watermelon
- Diagnosis of phenylketonuria
- History of hypotension, chronic uncontrolled hypertension, chronic kidney disease, diabetes, previous cardiac events or procedures,
- Smoking or other tobacco use
- Use of anticoagulant medications, cholesterol-lowering medications, vasodilatory dietary supplements (garlic, fish oil), or dietary supplements containing lycopene, ascorbic acid, L-glutamine, L-arginine, or L-citrulline
- Weight change > 10% in the previous six months
Data sourced from ClinicalTrials.gov (NCT03608254). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.