N/A N=52 Randomized Basic Science

Mindfulness and Neural Cardiovascular Control in Humans

Elevated Blood Pressure

Bottom Line

View on ClinicalTrials.gov: NCT03626363 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2024

Primary outcome: Primary: Muscle Sympathetic Nerve Activity — -2; -1 bursts per minute — p=0.51

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Stress Management (Behavioral)
Age: Adult · 18+ yrs
Sex: All
Sponsor: Michigan Technological University
Primary completion: Nov 2022

Outcome Measures

Outcome	Result	p-value
PRIMARY Muscle Sympathetic Nerve Activity	-2; -1	0.51
SECONDARY Arterial Stiffness	-0.04; -0.31	0.25

Summary

This study evaluates the impact of mindfulness-based stress reduction (MBSR) on sympathetic nerve activity and arterial stiffness. The investigator's central hypothesis is that MBSR will reduce sympathetic activity and arterial stiffness.

Eligibility Criteria

Inclusion Criteria

Seated systolic blood pressure >119 mmHg and/or diastolic blood pressure >79 mmHg
Body mass index <30 kg/m2

Exclusion Criteria

Smokers
Diabetes
Pregnant women
History of autonomic dysfunction
Cardiovascular medication

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03626363). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.