Phase 3
Completed N=114
Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o
Abortion, Spontaneous · Abortion in First Trimester · Pain Uterus · Abortion Early
Source: ClinicalTrials.gov NCT03636451 ↗
Enrolled (actual)
114
Serious AEs
0.0%
Results posted
Apr 2023
Primary outcomePrimary: Pain With Cervical Dilation — 52; 45 units on a scale
◆ Published Evidence
Emerging
4citations · ~1 / year
Effect of Paracervical Block Volume on Pain Control for Dilation and Aspiration: A Randomized Controlled Trial.
Summary
The investigators are conducting a study on pain control for dilation and curettage (D&C). Participants are eligible to enroll if they are a planning to have a D&C in a participating clinic. The investigators are studying how different ratios of medication to liquid affect pain when injected around the cervix. Both potential methods use the same dose of medication, though researchers would like to know which one works better. To be in this study, participants must be over the age of 18 with an early pregnancy loss or undesired pregnancy measuring less than 12 weeks gestation undergoing D&C while awake in clinic.
Linked Publications
-
Effect of Paracervical Block Volume on Pain Control for Dilation and Aspiration: A Randomized Controlled Trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain With Cervical Dilation |
52; 45 | — |
| SECONDARY Pain With Uterine Aspiration |
46; 58 | — |
| SECONDARY Pain 10 Minutes Post Procedure |
26; 11 | — |
| SECONDARY Overall Pain |
57; 56 | — |
Eligibility Criteria
Inclusion Criteria
- Women over the age of 18 presenting to UC San Diego and UC Los Angeles
- Undesired pregnancy or missed abortion < 11 weeks 6 days gestation
- Must speak English or Spanish
- Desire surgical termination of pregnancy or management of miscarriage in clinic
Exclusion Criteria
- Women with a diagnosis of inevitable or incomplete abortion
- Desire for general anesthesia or IV sedation
- Chronic pain conditions
- Any medical comorbidities that are a contraindication to performing the procedure in the clinic setting
- Allergy to or refusal of ketorolac, oral Versed, or a paracervical block
- If they have taken any pain medications the day of presentation to clinic
- If they have taken Misoprostol the day of presentation to clinic
Data sourced from ClinicalTrials.gov (NCT03636451) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.