N/A
Completed N=546
Inpatient Palliative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation
Stem Cell Transplant
Source: ClinicalTrials.gov NCT03641378 ↗
Enrolled (actual)
546
Serious AEs
0.0%
Results posted
Dec 2023
Primary outcomePrimary: Patient-reported Quality of Life (QOL): Functional Assessment of Cancer Therapy - Bone Marrow Transplant (FACT-BMT) — 94.69; 90.09 score on a scale
Summary
This research study is evaluating the impact of early involvement of a palliative care team working with the transplant oncology team will have on the quality of life, symptoms, and mood of patients undergoing stem cell transplantation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient-reported Quality of Life (QOL): Functional Assessment of Cancer Therapy - Bone Marrow Transplant (FACT-BMT) |
94.69; 90.09 | — |
| SECONDARY Patients' Quality of Life (QOL) Longitudinally: FACT-BMT |
107.8; 108.8 | — |
| SECONDARY Patients' Symptom Burden |
35.63; 39.86 | — |
| SECONDARY Patients' Fatigue |
28.3; 25.96 | — |
| SECONDARY Patients' Psychological Distress |
6.17; 6.63 | — |
| SECONDARY Patients' Depression |
6.70; 7.07 | — |
| SECONDARY Patients' Post-traumatic Stress Symptoms (PTSD) |
26.04; 28.17 | — |
| SECONDARY Caregiver QOL: CARGOQOL |
73.86; 73.51 | — |
| SECONDARY Caregiver Psychological Distress |
6.82; 7.84 | — |
| SECONDARY Caregiver Depression |
4.64; 4.73 | — |
Eligibility Criteria
Inclusion Criteria
Patient Inclusion Criteria
- adult patients (≥ 18 years) with hematologic malignancy admitted for autologous or allogeneic HCT.
- ability to read and respond to questions in English or Spanish or to complete questionnaires with assistance from an interpreter.
Caregiver Eligibility Criteria:
- adult (≥ 18 years) relative or a friend of a patient who agrees to participate in the study whom the patient identified as living with them or having in-person contact with him or her at least twice per week.
- ability to read and respond to questions in English or Spanish or to complete questionnaires with the assistance of an interpreter.
Exclusion Criteria
Patient Exclusion Criteria
- Patients undergoing HCT for benign hematologic conditions
- Patients undergoing outpatient HCT.
- Patients with psychiatric or cognitive conditions which the treating clinicians believes prohibits compliance with study procedures
Data sourced from ClinicalTrials.gov (NCT03641378). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.