N/A
Completed N=23
Variation in Urine Electrolytes, pH and Specific Gravity Throughout the Day
Healthy
Source: ClinicalTrials.gov NCT03645785 ↗
Enrolled (actual)
23
Serious AEs
0.0%
Results posted
Feb 2021
Primary outcomePrimary: Citrate/Creatinine Ratio — 0.658644; 0.584115; 0.562886; 0.540394 ratio
Summary
This study is a prospective study looking at healthy adults who will have urine collected at 4 set times throughout the course of the day. On Day 2, 3, and 4 subjects will drink a bottle of water containing True lemon and on days 2 and 3 double the amount of fluid intake from Day 1. On day 4 the subject will collect urine samples at 4 set times throughout the day. The pH of all of the urine samples will be checked with a urine dipstick and the samples will be sent to Litholink Lab for electrolyte composition analysis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Citrate/Creatinine Ratio |
0.658644; 0.584115; 0.562886; 0.540394; 0.490685; 0.441938 | — |
| PRIMARY Calcium / Creatinine |
0.162234; 0.161287; 0.137398; 0.140431; 0.126269; 0.111446 | — |
| PRIMARY pH |
6.52770; 6.32645; 6.34060; 6.37845; 6.43430; 6.24125 | — |
| PRIMARY Specific Gravity (SG) |
1.01725; 1.01525; 1.01725; 1.01850; 1.01950; 1.02051 | — |
| PRIMARY Total Fluid Intake |
2416.854; 2625.093; 3116.562; 3396.781 | — |
Eligibility Criteria
Inclusion Criteria
- Healthy adult subjects
Exclusion Criteria
- Subjects taking diuretics
- Subjects who have known kidney disease
- Subjects with history of known nephrolithiasis
Data sourced from ClinicalTrials.gov (NCT03645785). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.