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N/A N=80 Randomized Double-blind Treatment

Femoral Triangle and Adductor Canal Blocks Versus Femoral Nerve Block for Total Knee Arthroplasty

Total Knee Arthroplasty

Enrolled (actual)
80
Serious AEs
0.0%
Results posted
Jan 2021
Primary outcome: Primary: Extent of Motor Blockade — 18; 29; 13; 5 Participants — p=<0.01

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Femoral Nerve Block (Procedure); Femoral Triangle & Adductor Canal Blocks (Procedure)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Lithuanian University of Health Sciences
Primary completion
May 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Extent of Motor Blockade
18; 29; 13; 5; 1; 1 <0.01 sig
PRIMARY
Postoperative Pain Intensity and Pain Control
1.22; 0.45; 1.27; 1.45; 2.00; 2.10 >0.05
SECONDARY
Ability of Early Ambulation After Surgery
53.6; 53.7; 47.3; 36.9 >0.05
SECONDARY
Number of Participants Needing Additional Opioids
5; 3; 8; 13; 27; 23 >0.05
SECONDARY
Rate of Patients Satisfaction
8.8; 8.9; 8.5; 8.8; 8.1; 8.4 >0.05
SECONDARY
Number of Participants With Nausea or Vomiting
1; 1; 0; 0; 36; 39 >0.05

Summary

This prospective, double-blinded, randomized controlled study evaluates effects of femoral triangle and adductor canal blocks in comparison with femoral nerve block for primary total knee arthroplasty. Patients undergoing primary total knee arthroplasty will be randomly assigned to receive either femoral triangle and adductor canal blocks or femoral nerve block. Comparison of these two groups of patients will be based on the effects on postoperative pain control, extent of motor blockade, ability of early ambulation, patients satisfaction rates over the time of clinical recovery and the length of hospitalization. To the investigator's knowledge, no comparison has been made between femoral triangle and adductor canal blocks and femoral nerve block or any other block. Consequently, we hypothesized that femoral triangle and adductor canal blocks and femoral nerve block provide similar effects on postoperative pain control, but femoral triangle and adductor canal blocks are superior to femoral nerve block in terms of early postoperative mobilization.

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing primary unilateral total knee arthroplasty under the spinal anesthesia.
  • Age 18 - 90 years.
  • Patients conformed to American Society of Anesthesiologists (ASA) physical status I-III in preoperative assessment.
  • Ability to follow the study protocol.

Exclusion Criteria

  • Inability or refusal to follow the study protocol.
  • American Society of Anesthesiologists (ASA) physical status classification of IV or higher.
  • Coagulopathy.
  • Pre-existing lower extremity neuromuscular disorders.
  • Local infection over the injection site.
  • Allergy or contraindications to the drugs used in the study (local anesthetics, NSAIDs, opioids).
  • Chronic opioid use.
  • Other type of anesthesia.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03645954). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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