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Phase 4 Completed N=100 Randomized Quadruple-blind Treatment

Efficacy of Tranexamic Acid in Foot and Ankle Surgeries

Foot and Ankle Surgeries · Bunion
Source: ClinicalTrials.gov NCT03653429 ↗
Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Apr 2020
Primary outcomePrimary: Total Estimated Blood Loss — 40.41; 18.75 ml
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

Epidemiology of foot and ankle surgeries that present to the hospitals in the US are often underestimated. However there has been growing emphasis on identification of these injuries and practice patterns.

Outcome Measures

OutcomeResultp-value
PRIMARY
Total Estimated Blood Loss
40.41; 18.75
SECONDARY
Number of Participants With Wound Complications
8; 8; 8; 8
SECONDARY
Intra Operative Narcotic Consumption
93.37; 125.40
SECONDARY
Post Operative Narcotic Consumption
6.12; 10.10

Eligibility Criteria

Inclusion Criteria

  • ASA (American Society of Anesthesiology) class I-IV
  • age 8-75.

Exclusion Criteria

  • ASA class V
  • morbid obesity
  • patient refusal
  • patients with known coagulopathy disorder
  • renal insufficiency
  • hepatic dysfunction
  • serious cardiac disease
  • an allergy to TXA or receiving antiplatelet and /or anticoagulant drugs will be excluded.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03653429). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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