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N/A N=384 Randomized Treatment

Post-resection Treatment of Large Colon Polyps

Recurrence

Enrolled (actual)
384
Serious AEs
7.8%
Results posted
Jan 2024
Primary outcome: Primary: Recurrence — 10; 5; 24 Polyps

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Argon Plasma Coagulation (Device); Snare Tip Soft Coagulation (Device)
Age
Adult, Older Adult · 25+ yrs
Sex
All
Sponsor
Indiana University
Primary completion
Dec 2022

Outcome Measures

OutcomeResultp-value
PRIMARY
Recurrence
10; 5; 24
PRIMARY
Types of Recurrences
8; 5; 15; 2; 0; 8
SECONDARY
Time
4.08; 3.35; NA
SECONDARY
Complications
3; 4; 6; 0; 0; 0

Summary

Patients who have provided informed consented and are scheduled to undergo endoscopic mucosal resection (EMR) of lesions 15mm and larger will be randomized to STSC (80 W, Effect 5) vs APC (preferred settings) vs No Treatment of the perimeter of the EMR site.

Eligibility Criteria

Inclusion Criteria

  • 25 years and older
  • Ability to provide informed consent
  • Undergoing colonoscopy for screening, surveillance, diagnostic reasons, or removal of a lesion

Exclusion Criteria

  • Pedunculated lesions
  • Inflammatory bowel disease
  • Inability to provide informed consent
  • Lesions less than 15mm in largest dimension
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03654209). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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