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N/A N=198 Randomized Triple-blind Supportive Care

Effects of Digital Stories Intervention on Psychosocial Well-being

Bone Marrow Transplant · Information Disclosure · Hematopoietic Stem Cell Transplantation · Psychosocial Health · Depression

Enrolled (actual)
198
Serious AEs
0.0%
Results posted
Oct 2024
Primary outcome: Primary: Changes From Baseline Profile of Mood States (POMS) Short Version (Emotional Well-being or /Reduction of Emotional Distress) at 4 Weeks — 3.3; 3.4; 2.4; 2.8 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Baseline Surveys (Behavioral); Digital Stories Intervention (Behavioral); Information Control Intervention (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Arizona State University
Primary completion
Jan 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Changes From Baseline Profile of Mood States (POMS) Short Version (Emotional Well-being or /Reduction of Emotional Distress) at 4 Weeks
3.3; 3.4; 2.4; 2.8
SECONDARY
Changes From Baseline Emotional Well-being (Using the Emotional Acceptance Scale) at 4 Weeks
2.8; 2.8; 3.1; 3.0

Summary

Patients and caregivers undergoing hematopoietic stem cell transplantation often continue to experience anxiety, depression, isolation, and other psychosocial distress. A narrative-based digital stories intervention has shown promise in a pilot study with breast cancer patients in helping to alleviate emotional distress. This study is designed to test digital stories to be viewed and discussed by other HCT patients/caregivers as a psychosocial intervention in a randomized controlled trial and to test the effects of digital stories on how 110 patient and caregiver dyads (N=220) undergoing one of the most rigorous and aggressive treatments cope with treatment-related distress through supportive open dyadic communication and emotional expression.

Eligibility Criteria

Patient Inclusion Criteria:

  • age 18 or older
  • recently underwent Hematopoietic cell transplantation (HCT) (within a month after hospital discharge)
  • must be able to speak, read, and write in English
  • access to a working phone and e-mail account

Patient Exclusion Criteria:

  • no primary caregiver
  • cognitive impairment that prohibits completion of study assessment
  • visual or hearing impairment
  • other (e.g., provider non-approval or logistical constraints such as patient moving out of town)

Caregiver Inclusion Criteria:

  • age 18 or older
  • family caregivers who are identified as a primary caregiver by a patient
  • have primary responsibility for the care of patients throughout the HCT process
  • Must be able to speak, read, and write in English
  • Access to a working phone and e-mail account
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03654599). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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