N/A
N=62
Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents
Polypharmacy · Inappropriate Prescribing
Bottom Line
View on ClinicalTrials.gov: NCT03655405 ↗Enrolled (actual)
62
Serious AEs
12.9%
Results posted
May 2021
Primary outcome: Primary: Number of Inappropriate Medication at Follow-up — 4.35; 4.85 drugs — p=0.723
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Individual Deprescribing Intervention (Other)
- Age
- Older Adult · 65+ yrs
- Sex
- All
- Sponsor
- Anne Niquille
- Primary completion
- Aug 2019
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Inappropriate Medication at Follow-up |
4.35; 4.85 | 0.723 |
| SECONDARY Number of Potentially Inappropriate DDDs Prescribed to Participants at Follow-up |
2.73; 3.10 | 0.033 sig |
| SECONDARY Number of Chronic Drugs Prescribed to Participants |
9.68; 9.67 | 0.064 |
| SECONDARY Number of Chronic DDDs Prescribed to Participants |
7.82; 7.65 | 0.857 |
| SECONDARY Number of New Drugs Prescribed as a Result of the Intervention |
— | — |
| SECONDARY Health-related Quality of Life |
63.5; 65.4; 0.51; 0.61 | 0.769 |
| SECONDARY Number of Common Drug-related Complaints at Follow-up |
2.35; 1.44 | 0.212 |
Summary
This study will evaluate the effects of a pharmacist-led, deprescribing-focused medication review on the use of inappropriate medications by nursing home residents
Eligibility Criteria
Inclusion Criteria
- Take 5 or more prescribed drugs daily;
- Reside in the Nursing Home since at least 4 months.
Exclusion Criteria
- Physician judges that discussing deprescribing with them risks destabilising them.
Data sourced from ClinicalTrials.gov (NCT03655405). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.