N/A
Completed N=62
Peri-Transfusion QOL Assessments (PTQA): A New Paradigm of Transfusion Decision Support for Patients With MDS
Source: ClinicalTrials.gov NCT03660228 ↗Enrolled (actual)
62
Serious AEs
—
Results posted
Jun 2024
Primary outcomePrimary: Number of Participants With Receipt of Second Transfusion
Summary
This research study is evaluating how to best tailor blood transfusion decisions to match the quality of life changes experienced by individual patients with MDS.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Receipt of Second Transfusion |
— | — |
| PRIMARY Median Difference in Units pRBCs (for Those Transfusion-dependent) |
— | — |
| PRIMARY Number of Hospitalizations (for Both Transfusion Groups) |
— | — |
| PRIMARY Number of Clinic Visits (for Both Transfusion Groups) |
— | — |
| SECONDARY PTQA Utilization |
— | — |
| SECONDARY Number of Patients With Decisional Regret |
3 | — |
| SECONDARY Perceptions of Impact of PTQA on Care |
24 | — |
| SECONDARY Perceived Stress by the Associated Scales |
— | — |
Eligibility Criteria
Inclusion Criteria
- Age > 18 years of age
- Patients with MDS
- Patients approaching an Hb of 8.5 g/dL during enrollment period OR
- Patients with >1 transfusion scheduled during an 8-week period
- Ability to read and understand English
Exclusion Criteria
- Age 2
- Known CHF
- Unstable Angina
- Hb level below 7.5 g/dL or above 8.5 g/dL
- No plan for future transfusion.
- Patient enrollment will happen after patient has consented and scheduled their first/next transfusion.
- Patient will not be enrolled if no future transfusions are scheduled.
Data sourced from ClinicalTrials.gov (NCT03660228). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.