N/A
Completed N=60
Antimicrobial Efficacy of Four Different Irrigation Protocols
Dental Pulp Necrosis
Source: ClinicalTrials.gov NCT03668899 ↗
Enrolled (actual)
60
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcomePrimary: Number of Colony Forming Units Per Millilitre — 80300000; 79900000; 74000000; 73000000 CFU/ml
Summary
proper disinfection of root canal system before obturation is a must for long term success of endodontic treatment, therefore a proper irrigant is mandatory, therefore investigators are studying the antibacterial effects of 4 different irrgating solutions in root canal treatment of patients diagnosed with necrotic pulps in their mandibular posterior teeth. patients will be recruited from outpatient clinic of the endodontic department in cairo university. endodontic treatment will be carried out as usual and samples from the infected root canals will be collected before and after preparation to be cultivated and analyzed at the laboratories of microbiology of faculty of medicine, cairo university
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Colony Forming Units Per Millilitre |
80300000; 79900000; 74000000; 73000000; 77000; 124000 | — |
| SECONDARY Numerical Rating Scale |
7; 8; 6; 7; 8; 7 | — |
Eligibility Criteria
Inclusion Criteria
- Patient's age between 22-45 years.
- Both male and female.
- Patient who are medically free and with good health
- Necrotic Mandibular posterior teeth
Exclusion Criteria
- Pregnant females.
- Teeth with vital inflamed pulps, symptomatic periapical abscess and facial cellulitis, periodontally diseased and hopeless teeth.
- Teeth with previous fillings and/ or previous endodontic treatment
Data sourced from ClinicalTrials.gov (NCT03668899). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.