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N/A N=242 Randomized Single-blind Treatment

Evaluate the Safety and Effectiveness of the Biotrue ONEday for Astigmatism

Astigmatism

Enrolled (actual)
242
Serious AEs
0.0%
Results posted
Dec 2020
Primary outcome: Primary: Proportion of Participants Achieving a Contact Lens Corrected Distance logMAR VA of 0.04 or Better — 105; 92 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Control (Device); Test (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Bausch & Lomb Incorporated
Primary completion
Dec 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Proportion of Participants Achieving a Contact Lens Corrected Distance logMAR VA of 0.04 or Better
105; 92

Summary

Comparing Test Lens for Astigmatism Soft Contact Lens (Test) to 1-Day Control for Astigmatism contact lenses (Control).

Eligibility Criteria

Inclusion Criteria

  • Subject must be of legal age (at least 18 or as defined by state law) on the date the ICF is signed and have the capacity to provide voluntary informed consent.
  • Subject must be able to read, understand and provide written informed consent on the IRB approved ICF and provide authorization as appropriate for local privacy regulations.
  • Subject must have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings (greater than Grade 1 and/or presence of infiltrates) and have clear central 6 mm corneas.
  • Subject must be an adapted wearer of soft contact lenses, wear a lens in each eye, and each lens must be of the same manufacture and brand.

Exclusion Criteria

  • Subject has worn gas permeable (GP) contact lenses within last 30 days or polymethylmethacrylate (PMMA) lenses within last 3 months.
  • Subject has systemic disease affecting ocular health.
  • Subject is using any systemic or topical medications that will affect ocular physiology or lens performance.
  • Subject has an active ocular disease (for example but not limited to papillary conjunctivitis, any conjunctivitis: viral, bacterial, allergic), any corneal infiltrative response or are using any ocular medications.
  • Subject has any "Present" finding during the slit lamp examination that, in the Investigator's judgment, interferes with contact lens wear
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03681808). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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