N/A
Completed N=56
Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
Source: ClinicalTrials.gov NCT03688542 ↗Enrolled (actual)
56
Serious AEs
—
Results posted
Apr 2021
Primary outcomePrimary: Percentage of Potentially Inappropriate Galenic Units — 24; 23 percent — p=<0.05
Summary
Older people residing in nursing homes (NH) are frequently polymedicated and often prescribed potentially inappropriate medications. Deprescribing has been proposed as a way to reduce the number of drugs they receive and their exposure to harmful treatments.
The objectives of this study are 1) To evaluate the effect of a deprescribing-specific interdisciplinary quality circle module on the use of potentially inappropriate medication in nursing-home residents. 2) To determine the effective strategies to reach and implement deprescribing consensus resulting of said quality circle module.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Potentially Inappropriate Galenic Units |
24; 23 | <0.05 sig |
| PRIMARY Number of Potentially Inappropriate Defined Daily Doses (DDDs) Per Average Resident and Per Day |
2.1; 2.3 | <0.05 sig |
| SECONDARY Number of Potentially Inappropriate DDD to Avoid |
0.3; 0.3 | <0.05 sig |
| SECONDARY Number of Potentially Inappropriate DDD to Reevaluate |
1.8; 2.0 | <0.05 sig |
| SECONDARY Number of Hospital Days |
3.1; 2.5 | <0.05 sig |
| SECONDARY Mortality Rate |
31; 38 | <0.05 sig |
| SECONDARY Number of Falls Per Average Resident and Per Year |
3.0; 2.6 | <0.05 sig |
| SECONDARY Percentage of Residents With at Least One Day of Physical Restraints Use |
33; 37 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
Nursing homes taking part in the study must have
- a geriatric of psycho-geriatric mission;
- been part of their cantonal pharmaceutical assistance program for at least a year.
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT03688542). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.