N/A
N=56
Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
Polypharmacy · Inappropriate Prescribing
Bottom Line
View on ClinicalTrials.gov: NCT03688542 ↗Enrolled (actual)
56
Serious AEs
—
Results posted
Apr 2021
Primary outcome: Primary: Percentage of Potentially Inappropriate Galenic Units — 24; 23 percent — p=<0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Quality Circle Deprescribing Module (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- Anne Niquille
- Primary completion
- Jul 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage of Potentially Inappropriate Galenic Units |
24; 23 | <0.05 sig |
| PRIMARY Number of Potentially Inappropriate Defined Daily Doses (DDDs) Per Average Resident and Per Day |
2.1; 2.3 | <0.05 sig |
| SECONDARY Number of Potentially Inappropriate DDD to Avoid |
0.3; 0.3 | <0.05 sig |
| SECONDARY Number of Potentially Inappropriate DDD to Reevaluate |
1.8; 2.0 | <0.05 sig |
| SECONDARY Number of Hospital Days |
3.1; 2.5 | <0.05 sig |
| SECONDARY Mortality Rate |
31; 38 | <0.05 sig |
| SECONDARY Number of Falls Per Average Resident and Per Year |
3.0; 2.6 | <0.05 sig |
| SECONDARY Percentage of Residents With at Least One Day of Physical Restraints Use |
33; 37 | <0.05 sig |
Summary
Older people residing in nursing homes (NH) are frequently polymedicated and often prescribed potentially inappropriate medications. Deprescribing has been proposed as a way to reduce the number of drugs they receive and their exposure to harmful treatments.
The objectives of this study are 1) To evaluate the effect of a deprescribing-specific interdisciplinary quality circle module on the use of potentially inappropriate medication in nursing-home residents. 2) To determine the effective strategies to reach and implement deprescribing consensus resulting of said quality circle module.
Eligibility Criteria
Inclusion Criteria
Nursing homes taking part in the study must have
- a geriatric of psycho-geriatric mission;
- been part of their cantonal pharmaceutical assistance program for at least a year.
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT03688542). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.