N/A
N=41
Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)
Post Traumatic Stress Disorder · Problem Drinking
Bottom Line
View on ClinicalTrials.gov: NCT03703258 ↗Enrolled (actual)
41
Serious AEs
0.0%
Results posted
Dec 2022
Primary outcome: Primary: Problem Drinking Scores at Baseline and 3 Weeks — 12.40; 11.00; 10.16; 7.62 score on a scale — p=.60
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- App-based intervention (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- University of Washington
- Primary completion
- Aug 2021
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Problem Drinking Scores at Baseline and 3 Weeks |
12.40; 11.00; 10.16; 7.62 | .60 |
| PRIMARY Problem Drinking Scores at Baseline and 3 Months |
12.40; 11.00; 5.75; 5.55 | .94 |
| PRIMARY Posttraumatic Stress Symptom Severity Score at Baseline and 3 Weeks |
46.60; 39.81; 36.53; 35.62 | .38 |
| PRIMARY Posttraumatic Stress Symptom Severity Score at Baseline and 3 Months |
46.60; 39.81; 22.10; 25.30 | .04 sig |
| SECONDARY Anxiety |
13.35; 12.14; 11.32; 11.33; 9.05; 8.80 | .51 |
| SECONDARY Coping Self-efficacy |
3.59; 4.00; 4.31; 4.15; 4.96; 5.08 | .04 sig |
| SECONDARY Depression |
14.30; 10.81; 11.26; 10.14; 9.16; 7.65 | .13 |
| SECONDARY Alcohol Consumption (Quantity) |
9.35; 11.10; 7.68; 9.57; 6.25; 7.70 | .85 |
| SECONDARY Alcohol Consumption (Frequency) |
2.90; 2.76; 2.37; 2.47; 2.30; 2.35 | .75 |
| SECONDARY Alcohol Consumption (Hours) |
8.15; 8.33; 6.84; 7.14; 5.75; 10.15 | .86 |
Summary
Sexual assault victimization is a common and particularly harmful form of trauma that is associated with increased risk for high-risk drinking and other conditions of public health concern, such as PTSD. Given evidence that sexual assault survivors who have low social support or receive negative social reactions to sexual assault disclosure are more likely to experience PTSD and drinking problems, improving social support is a novel target for intervention. The proposed study will attempt to prevent the onset of high-risk drinking and PTSD in sexual assault survivors by developing and testing a web-based early intervention aimed at increasing contact with social supporters and mitigating the harm of negative social reactions; ultimately, results will contribute to advancing the field's understanding of the potential for social support to mitigate the harm of trauma.
Eligibility Criteria
Inclusion Criteria
- informed consent
- self-identification as female
- sexual assault, defined as endorsement of unwanted, attempted or completed sexual contact in the past 10 weeks
- age > 18
- English fluency
- smartphone and internet access at least daily for 3 weeks and at least weekly for 3 months
- consumption of >1 alcoholic drink in the past month
- >1 episode of high-risk drinking in past 6 months, defined as either more than 3 drinks on a given day or more than 7 drinks in a given week
- at least 3 symptom clusters endorsed on the PTSD Checklist.
Exclusion Criteria
- active suicidality
- psychosis
Data sourced from ClinicalTrials.gov (NCT03703258). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.