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N/A N=60 Randomized Treatment

Project EQuIP: Empowering Queer Identities in Psychotherapy

Sexual Minority Stress

Enrolled (actual)
60
Serious AEs
1.1%
Results posted
Oct 2021
Primary outcome: Primary: Depression — 27.57; 29.70; 26.86; 20.44 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
EQuIP (Empowering Queer Identities in Psychotherapy) (Behavioral)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Yale University
Primary completion
Jul 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
Depression
27.57; 29.70; 26.86; 20.44; 24.83; 19.00
PRIMARY
Brief Symptom Inventory
1.80; 1.74; 1.85; 1.38; 1.64; 1.16
PRIMARY
Alcohol Use
3.93; 3.63; 3.34; 2.16; 2.80; 1.92
SECONDARY
Overall Depression Severity and Impairment Scale
6.17; 6.30; 7.69; 4.09; 5.85; 3.88
SECONDARY
Overall Anxiety Severity and Impairment Scale
8.20; 8.80; 8.03; 6.00; 6.08; 6.17
SECONDARY
Suicidal Ideation Attributes Scale
5.03; 4.13; 5.59; 2.09; 2.73; 1.46
SECONDARY
Lesbian, Gay, and Bisexual Identity Scale-Internalized Homonegativity Subscale
1.49; 1.72; 1.32; 1.63; 1.36; 1.49

Summary

The aim of this study is to develop an evidence-based psychosocial intervention for sexual minority women. This intervention will specifically target the adverse mental and behavioral health outcomes disproportionately experienced by sexual minority women, including depression, suicidality, and alcohol abuse, which are known to be driven by stigma-related stressors associated with their sexual orientation (i.e., minority stress processes).

Eligibility Criteria

For Phase 3

Inclusion Criteria

  • sexual minority status operationalized as identity (e.g., lesbian, bisexual, pansexual, queer)
  • aged 18-35
  • self-identification as a woman with the option of selecting multiple gender identities
  • symptoms of anxiety or depression within the past 90 days (≥ 2.5 on the BSI-4 for either anxiety or depression)
  • at least one instance of past-90-day heavy drinking (i.e., ≥ 4 drinks in one sitting)
  • 6-month NYC residential stability and availability
  • English fluency

Exclusion Criteria

  • active psychosis or active mania
  • active suicidality or active homicidality
  • currently in mental health treatment exceeding one day per month
  • having received any cognitive-behavioral therapy treatment in the past 12 months
  • evidence of gross cognitive impairment
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03721276). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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