N/A
N=67
Novel Executive Function Training for Obesity
Overweight and Obesity
Bottom Line
View on ClinicalTrials.gov: NCT03724396 ↗Enrolled (actual)
67
Serious AEs
0.0%
Results posted
Feb 2024
Primary outcome: Primary: Feasibility as Measured by Attendance — 18; 18 Sessions
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Behavioral Weight Loss - BWL (Behavioral); Novel Executive Function Training - NEXT (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, San Diego
- Primary completion
- Jan 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Feasibility as Measured by Attendance |
18; 18 | — |
| PRIMARY Acceptability |
25; 26; 28; 24 | — |
Summary
Currently, the best behavioral treatments for obesity only work for 50% of adults, and of those who initially succeed, most do not maintain their weight loss. One reason for this failure may be due to neurocognitive deficits found among individuals with obesity, particularly related to executive function, which make it difficult for these adults to adhere to treatment recommendations. The proposed study aims to develop a Novel Executive Function Treatment (NEXT), which when administered prior to the behavioral treatment, could help improve outcomes by addressing the neurocognitive deficits in adults with overweight or obesity.
Eligibility Criteria
Inclusion Criteria
- Age 18-65
- Ability to read English at a 6th grade level
- BMI >25 and ≤45
- Difficulties with executive functioning
Exclusion Criteria
- Medical condition that requires physician monitoring to participate in weight control program or prohibits safely participating in recommended physical activity
- Psychiatric condition that could interfere with program participant (e.g., substance abuse, suicide attempt within previous 6 months, active purging)
- Currently pregnant, lactating or plan to be in the timespan of program follow-up
- Current enrollment in an organized weight control program
- Change in psychotropic medication or other medication that could have impact on weight during the previous 3 months
- History of bariatric surgery
- History of learning disorder, neurological condition or injury
Data sourced from ClinicalTrials.gov (NCT03724396). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.