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Phase 2 Completed N=18 Diagnostic

Ga-DOTATATE PET for Phosphaturic Mesenchymal Tumors in Patients With Tumor Induced Osteomalacia

Osteomalacia
Source: ClinicalTrials.gov NCT03736564 ↗
Enrolled (actual)
18
Serious AEs
0.0%
Results posted
Apr 2025
Primary outcomePrimary: Number of Participants With Positive Localization of Phosphaturic Mesenchymal Tumors (PMTs) — 15 Participants

Summary

The researchers are trying to evaluate a newer imaging technique (Ga-DOTATATE PET/CT) to see if it is more sensitive to localize the source of the hormone, which has caused the low phosphate levels.

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Positive Localization of Phosphaturic Mesenchymal Tumors (PMTs)
15

Eligibility Criteria

Inclusion Criteria

  • Adults (18 years of age or older) seen at Mayo Clinic, Rochester for FGF23 mediated osteomalacia between 1/1/2000 and 1/30/2018 who provide informed consent to participate in the study.

Exclusion Criteria

  • Pregnant
  • Prisoners
  • Subjects diagnosed with heritable hypophosphatemic rickets/osteomalacia
  • Subjects who do not consent for the study or withdraw consent during the duration of the study.
  • Subjects in whom tumor localization and successful resection has already occurred.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03736564). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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