Medication Adherence Clinical Decision Support
Hyperlipidemia · Hypertension · Diabetes · Medication Nonadherence
Bottom Line
View on ClinicalTrials.gov: NCT03748420 ↗Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Adherence Intervention (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- HealthPartners Institute
- Primary completion
- Oct 2022
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Blood Pressure Medication Adherence |
396; 470 | 0.0103 sig |
| PRIMARY Non-Insulin Glycemic Medication Adherence |
279; 296 | 0.7967 |
| PRIMARY Statin Medication Adherence |
529; 586 | 0.0589 |
| PRIMARY Mean Change in Systolic Blood Pressure |
-15.2; -13.8 | 0.21 |
| PRIMARY Mean Change in A1c |
-1.1; -1.2 | 0.20 |
| SECONDARY Clinic-based Medical Care Costs |
1210.15; 1202.68 | 0.901 |
Summary
Eligibility Criteria
Inclusion Criteria
- One or more of the following clinical criteria:
A. In the 12 months prior to the index visit, most recent hemoglobin A1C ≥8% AND have one or more active non-insulin glycemic medications on their electronic health record (EHR) medication list AND a potential adherence issue for one or more of these medications based on the Epic Medication Adherence score (e-PDC 21 with atherosclerotic cardiovascular disease (ASCVD) identified by a cardiovascular disease (CVD) diagnosis on the problem list or two or more International Classification of Diseases (ICD)-10 diagnostic codes in the last 2 years
- Age >21 and LDL >190 mg/dL
- Aged 40 to 75 AND diabetes identified by the diagnosis on the problem list or two or more ICD-10 diagnostic codes in the last 2 years
- Aged 40 to 75 with 10-year CV Risk Score >7.5% based on the ACC/AHA 10-year ASCVD risk equation.
Exclusion Criteria
An individual who meets any of the following criteria will be excluded from the study analysis:
- Patients enrolled in hospice,
- Patients with active cancer or undergoing chemotherapy
- Patients with pregnancy in the last year
- Patients without HealthPartners insurance coverage for at least 11 of the 12 months before the index visit will be excluded from cost analysis.
- For Statin cohort, ≥1 LDL result <100 mg/dl within 2 years
Data sourced from ClinicalTrials.gov (NCT03748420). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.