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N/A N=574 Randomized Single-blind Screening

Targeting of UnControlled Hypertension in Emergency Department

Hypertension · Cardiovascular Diseases · Vascular Diseases

Enrolled (actual)
574
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Mean Systolic Blood Pressure (SBP) Difference at 6 Months Post-intervention Compared to Usual Care. — -9.2; -14.0 mmHg

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
HTN Educational Video (Other); Visual Echocardiogram Image Clips (Other); Mobile Health and Remote BP monitoring (Other); Post-Acute Care HTN Transition consultation (PACHT-c) (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Illinois at Chicago
Primary completion
Mar 2023

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Systolic Blood Pressure (SBP) Difference at 6 Months Post-intervention Compared to Usual Care.
-9.2; -14.0
SECONDARY
Mean Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) Differences at 3 Months Post-intervention Compared to Usual Care.
-9.8; -14; -1.5; -2.4
SECONDARY
Diastolic Blood Pressure (DBP) Difference at 6 Months Post-intervention Compared to Usual Care.
-1.3; -3.3

Summary

The proposed project underscores the following: 1) The prevalence of uncontrolled/undiagnosed hypertension (HTN) in underrepresented groups presenting to the ED is alarmingly high, and 2) ED engagement and early risk assessment/stratification is a cost-effective, feasible innovation to help close health disparity gaps in HTN. This proposal involves a two-arm randomized controlled trial of up to 770 patients from the Emergency Department at University of Illinois Hospital with elevated blood pressure (BP). The primary objective is to determine the effectiveness of an emergency department-initiated Educational and Empowerment (E2) intervention with a Post Acute Care Hypertension Consultation (PACHT-c) intervention (arm 2) on the primary outcome of mean systolic blood pressure (SBP) differences between the two trial arms at 6-months post intervention. Secondary objectives include evaluating the effectiveness of this ED education and empowerment intervention on mean SBP and diastolic blood pressure (DBP) differences at 3-months, and mean DBP differences at 6-months.

Eligibility Criteria

Inclusion Criteria

  • BP>=140/90 and <=180/110 mm Hg at time of discharge from ED
  • Verbal fluency in English or Spanish
  • Age 18-75 years

Exclusion Criteria

  • Unable to verbalize comprehension of study, impaired decision-making or documented dementia
  • Plans to move from Chicago area within the next year
  • Pregnant or trying to get pregnant
  • COVID-19 positive within the past 14 days
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT03749499). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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