N/A
N=574
Targeting of UnControlled Hypertension in Emergency Department
Hypertension · Cardiovascular Diseases · Vascular Diseases
Bottom Line
View on ClinicalTrials.gov: NCT03749499 ↗Enrolled (actual)
574
Serious AEs
0.0%
Results posted
Jun 2025
Primary outcome: Primary: Mean Systolic Blood Pressure (SBP) Difference at 6 Months Post-intervention Compared to Usual Care. — -9.2; -14.0 mmHg
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- HTN Educational Video (Other); Visual Echocardiogram Image Clips (Other); Mobile Health and Remote BP monitoring (Other); Post-Acute Care HTN Transition consultation (PACHT-c) (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Illinois at Chicago
- Primary completion
- Mar 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Mean Systolic Blood Pressure (SBP) Difference at 6 Months Post-intervention Compared to Usual Care. |
-9.2; -14.0 | — |
| SECONDARY Mean Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) Differences at 3 Months Post-intervention Compared to Usual Care. |
-9.8; -14; -1.5; -2.4 | — |
| SECONDARY Diastolic Blood Pressure (DBP) Difference at 6 Months Post-intervention Compared to Usual Care. |
-1.3; -3.3 | — |
Summary
The proposed project underscores the following: 1) The prevalence of uncontrolled/undiagnosed hypertension (HTN) in underrepresented groups presenting to the ED is alarmingly high, and 2) ED engagement and early risk assessment/stratification is a cost-effective, feasible innovation to help close health disparity gaps in HTN. This proposal involves a two-arm randomized controlled trial of up to 770 patients from the Emergency Department at University of Illinois Hospital with elevated blood pressure (BP). The primary objective is to determine the effectiveness of an emergency department-initiated Educational and Empowerment (E2) intervention with a Post Acute Care Hypertension Consultation (PACHT-c) intervention (arm 2) on the primary outcome of mean systolic blood pressure (SBP) differences between the two trial arms at 6-months post intervention. Secondary objectives include evaluating the effectiveness of this ED education and empowerment intervention on mean SBP and diastolic blood pressure (DBP) differences at 3-months, and mean DBP differences at 6-months.
Eligibility Criteria
Inclusion Criteria
- BP>=140/90 and <=180/110 mm Hg at time of discharge from ED
- Verbal fluency in English or Spanish
- Age 18-75 years
Exclusion Criteria
- Unable to verbalize comprehension of study, impaired decision-making or documented dementia
- Plans to move from Chicago area within the next year
- Pregnant or trying to get pregnant
- COVID-19 positive within the past 14 days
Data sourced from ClinicalTrials.gov (NCT03749499). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.